QUODD

Insider Transactions last 24 months for Lyra Therapeutics, Inc. - OTC: LYRA

Transactions
All	Buy	Sell	Option Exercise

Filer's Name	Relationship/ Title	Trans. Date	Trans. Type	Ownership Type	Security Type	Shares	Price	Trans. Value	Total Shares Owned
Palasis Maria	President & CEO	01/06/2026	DS	Direct	COM	1,702	$3.36	$5,725.53	1,096,733
Cavalier Jason	Chief Financial Officer	01/06/2026	DS	Direct	COM	769	$3.36	$2,586.92	518,547
Perceptive Advisors Llc	Other	11/13/2025	DS	Indirect	COM	3,213	$3.90	$12,531.02	14,026
Perceptive Advisors Llc	Other	11/13/2025	DS	Indirect	COM	28,597	$3.90	$111,531.16	124,859
Perceptive Advisors Llc	Other	11/12/2025	DS	Indirect	COM	883	$4.06	$3,584.45	17,239
Perceptive Advisors Llc	Other	11/12/2025	DS	Indirect	COM	7,862	$4.06	$31,915.00	153,456
Perceptive Advisors Llc	Other	11/11/2025	DS	Indirect	COM	537	$4.31	$2,316.94	18,122
Perceptive Advisors Llc	Other	11/11/2025	DS	Indirect	COM	4,783	$4.31	$20,636.73	161,318
Perceptive Advisors Llc	Other	11/10/2025	DS	Indirect	COM	1,869	$4.54	$8,484.89	18,659
Perceptive Advisors Llc	Other	11/10/2025	DS	Indirect	COM	16,633	$4.54	$75,510.49	166,101
Perceptive Advisors Llc	Other	11/07/2025	DS	Indirect	COM	1,993	$4.75	$9,460.17	20,528
Perceptive Advisors Llc	Other	11/07/2025	DS	Indirect	COM	17,746	$4.75	$84,234.94	182,734
Perceptive Advisors Llc	Other	11/06/2025	DS	Indirect	COM	3,247	$5.18	$16,819.14	22,521
Perceptive Advisors Llc	Other	11/06/2025	DS	Indirect	COM	28,902	$5.18	$149,709.47	200,480
Cavalier Jason	Chief Financial Officer	07/10/2025	DS	Direct	COM	684	$8.91	$6,094.44	519,316
Palasis Maria	President & CEO	07/10/2025	DS	Direct	COM	1,565	$8.91	$13,944.15	1,098,435
Cavalier Jason	Chief Financial Officer	01/08/2025	AA	Direct	COM	420,000	$0.00	$0.00	520,000
Palasis Maria	President & CEO	01/08/2025	AA	Direct	COM	800,000	$0.00	$0.00	1,100,000
Cavalier Jason	Chief Financial Officer	10/16/2024	AA	Direct	COM	100,000	$0.00	$0.00	100,000
Palasis Maria	President & CEO	10/16/2024	AA	Direct	COM	300,000	$0.00	$0.00	300,000

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Transaction Type Key First letter: A = Acquired, D = Disposed Second letter: A = Grant, award or other acquisition pursuant to Rule 16b-3(d) C = Conversion of derivative security \| D = Disposition to the issuer of issuer equity securities pursuant to Rule 16b-3(e) \| E = Expiration of short derivative position \| F = Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3. \| G = Gift \| H = Expiration (or cancellation) of long derivative position with value received \| I = Discretionary transaction in accordance with Rule 16b-3(f) \| J = Other \| L = Small acquisition under Rule 16a-6 \| M = Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 \| O = Exercise of out-of-the-money derivative security \| P = Open market or private purchase \| S = Open market or private sale \| U = Disposition pursuant to a tender of shares in a change of control transaction \| W = Acquisition or disposition by will or the laws of descent and distribution \| X = Exercise of in-the-money or at-the-money derivative security \| Z = Deposit into or withdrawal from voting trust		Send to Excel

Transaction Type Key
First letter: A = Acquired, D = Disposed
Second letter:
A = Grant, award or other acquisition pursuant to Rule 16b-3(d) C = Conversion of derivative security | D = Disposition to the issuer of issuer equity securities pursuant to Rule 16b-3(e) | E = Expiration of short derivative position | F = Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3. | G = Gift | H = Expiration (or cancellation) of long derivative position with value received | I = Discretionary transaction in accordance with Rule 16b-3(f) | J = Other | L = Small acquisition under Rule 16a-6 | M = Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 | O = Exercise of out-of-the-money derivative security | P = Open market or private purchase | S = Open market or private sale | U = Disposition pursuant to a tender of shares in a change of control transaction | W = Acquisition or disposition by will or the laws of descent and distribution | X = Exercise of in-the-money or at-the-money derivative security | Z = Deposit into or withdrawal from voting trust

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