QUODD

Insider: PERCEPTIVE ADVISORS LLC

Company Holdings	All	LYRA	OBIO	ACRV	ALDX	SLDB	MGTX	VRCA	SLNO	CRNX	NAUT	RAIN	ADMA	VYNE	SCYX	MOTS	FOLD	RPRX

Company Holdings

All

LYRA

OBIO

ACRV

ALDX

SLDB

MGTX

VRCA

SLNO

CRNX

NAUT

RAIN

ADMA

VYNE

SCYX

MOTS

FOLD

RPRX

	Direct	Indirect Ownership	Total
Shares	497,038	111,989,098	112,486,136
Value	$1,642,710.59	$1,201,191,736.36	$1,202,834,446.95

Ticker	Trans. Date	Trans. Type	Shares	Ownership Type	Issue Type	Price	Trans. Value	Total Shares Owned
LYRA	11/13/2025	DDS	3,213	Indirect	COM	$3.90	$12,531.02	14,026
LYRA	11/13/2025	DDS	28,597	Indirect	COM	$3.90	$111,531.16	124,859
LYRA	11/12/2025	DDS	7,862	Indirect	COM	$4.06	$31,915.00	153,456
LYRA	11/12/2025	DDS	883	Indirect	COM	$4.06	$3,584.45	17,239
LYRA	11/11/2025	DDS	4,783	Indirect	COM	$4.31	$20,636.73	161,318
LYRA	11/11/2025	DDS	537	Indirect	COM	$4.31	$2,316.94	18,122
LYRA	11/10/2025	DDS	16,633	Indirect	COM	$4.54	$75,510.49	166,101
LYRA	11/10/2025	DDS	1,869	Indirect	COM	$4.54	$8,484.89	18,659
LYRA	11/07/2025	DDS	17,746	Indirect	COM	$4.75	$84,234.94	182,734
LYRA	11/07/2025	DDS	1,993	Indirect	COM	$4.75	$9,460.17	20,528
LYRA	11/06/2025	DDS	28,902	Indirect	COM	$5.18	$149,709.47	200,480
LYRA	11/06/2025	DDS	3,247	Indirect	COM	$5.18	$16,819.14	22,521
OBIO	08/01/2025	AAP	700,000	Indirect	COM	$2.75	$1,925,000.00	5,292,556
ACRV	05/01/2025	DDS	298,886	Indirect	COM	$1.34	$400,507.24	3,104,139
ACRV	04/30/2025	DDS	437,881	Indirect	COM	$1.41	$617,412.21	3,403,025
ACRV	04/29/2025	DDS	250,000	Indirect	COM	$1.41	$352,500.00	3,840,906
ACRV	04/28/2025	DDS	215,283	Indirect	COM	$1.56	$335,841.48	4,090,906
ACRV	04/25/2025	DDS	1,054,669	Indirect	COM	$1.95	$2,056,604.55	4,306,189
ALDX	04/03/2025	DDS	3,400,000	Indirect	COM	$1.42	$4,828,000.00	5,875,851
SLDB	02/19/2025	AAP	5,000,000	Indirect	COM	$4.03	$20,150,000.00	11,833,539
MGTX	08/12/2024	AAP	1,250,000	Indirect	COM	$4.00	$5,000,000.00	12,531,103
ACRV	04/11/2024	AAP	2,353,000	Indirect	COM	$8.50	$20,000,500.00	5,360,858
ALDX	04/05/2024	AAP	37,712	Indirect	COM	$4.74	$178,754.88	9,275,851
ALDX	04/04/2024	AAP	140,281	Indirect	COM	$4.67	$655,112.27	9,238,139
ALDX	04/03/2024	AAP	309,847	Indirect	COM	$4.09	$1,267,274.23	9,097,858

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Trans. Date	Trans. Type	Shares	Ownership Type	Issue Type	Price	Trans. Value	Total Shares Owned
11/13/2025	DDS	3,213	Indirect	COM	$3.90	$12,531.02	14,026
11/13/2025	DDS	28,597	Indirect	COM	$3.90	$111,531.16	124,859
11/12/2025	DDS	7,862	Indirect	COM	$4.06	$31,915.00	153,456
11/12/2025	DDS	883	Indirect	COM	$4.06	$3,584.45	17,239
11/11/2025	DDS	4,783	Indirect	COM	$4.31	$20,636.73	161,318
11/11/2025	DDS	537	Indirect	COM	$4.31	$2,316.94	18,122
11/10/2025	DDS	16,633	Indirect	COM	$4.54	$75,510.49	166,101
11/10/2025	DDS	1,869	Indirect	COM	$4.54	$8,484.89	18,659
11/07/2025	DDS	17,746	Indirect	COM	$4.75	$84,234.94	182,734
11/07/2025	DDS	1,993	Indirect	COM	$4.75	$9,460.17	20,528
11/06/2025	DDS	28,902	Indirect	COM	$5.18	$149,709.47	200,480
11/06/2025	DDS	3,247	Indirect	COM	$5.18	$16,819.14	22,521
05/31/2023	AAP	3,610,832	Indirect	COM	$2.49	$8,999,998.76	11,469,117
04/12/2022	AAP	5,924,170	Indirect	COM	$4.22	$24,999,997.40	7,858,285
05/05/2020	AAP	625,000	Indirect	COM	$16.00	$10,000,000.00	1,934,115

Trans. Date	Trans. Type	Shares	Ownership Type	Issue Type	Price	Trans. Value	Total Shares Owned
08/01/2025	AAP	700,000	Indirect	COM	$2.75	$1,925,000.00	5,292,556

Trans. Date	Trans. Type	Shares	Ownership Type	Issue Type	Price	Trans. Value	Total Shares Owned
05/01/2025	DDS	298,886	Indirect	COM	$1.34	$400,507.24	3,104,139
04/30/2025	DDS	437,881	Indirect	COM	$1.41	$617,412.21	3,403,025
04/29/2025	DDS	250,000	Indirect	COM	$1.41	$352,500.00	3,840,906
04/28/2025	DDS	215,283	Indirect	COM	$1.56	$335,841.48	4,090,906
04/25/2025	DDS	1,054,669	Indirect	COM	$1.95	$2,056,604.55	4,306,189
04/11/2024	AAP	2,353,000	Indirect	COM	$8.50	$20,000,500.00	5,360,858

Trans. Date	Trans. Type	Shares	Ownership Type	Issue Type	Price	Trans. Value	Total Shares Owned
04/03/2025	DDS	3,400,000	Indirect	COM	$1.42	$4,828,000.00	5,875,851
04/05/2024	AAP	37,712	Indirect	COM	$4.74	$178,754.88	9,275,851
04/04/2024	AAP	140,281	Indirect	COM	$4.67	$655,112.27	9,238,139
04/03/2024	AAP	309,847	Indirect	COM	$4.09	$1,267,274.23	9,097,858
04/02/2024	AAP	186,051	Indirect	COM	$3.44	$640,015.44	8,788,011
04/01/2024	AAP	8,374	Indirect	COM	$3.25	$27,215.50	8,601,960
10/18/2023	DDS	306,499	Indirect	COM	$1.74	$533,308.26	8,593,586
10/16/2023	DDS	2,450,000	Indirect	COM	$1.60	$3,920,000.00	8,900,085
08/10/2022	AAP	15,000	Indirect	COM	$7.85	$117,750.00	11,350,085
08/09/2022	AAP	100,000	Indirect	COM	$7.50	$750,000.00	11,335,085
08/08/2022	AAP	97,000	Indirect	COM	$7.24	$702,280.00	11,235,085
08/05/2022	AAP	141,000	Indirect	COM	$6.95	$979,950.00	11,138,085
08/04/2022	AAP	95,100	Indirect	COM	$6.17	$586,767.00	10,997,085
08/03/2022	AAP	100,000	Indirect	COM	$5.84	$584,000.00	10,901,985
08/02/2022	AAP	412,406	Indirect	COM	$5.59	$2,305,349.54	10,801,985
08/01/2022	AAP	144,185	Indirect	COM	$5.05	$728,134.25	10,389,579
07/29/2022	AAP	222,123	Indirect	COM	$5.03	$1,117,278.69	10,245,394
07/28/2022	AAP	119,392	Indirect	COM	$5.00	$596,960.00	10,023,271
05/03/2021	AAP	1,200,000	Indirect	COM	$12.50	$15,000,000.00	9,903,879
01/19/2021	AAP	1,368,421	Indirect	COM	$9.50	$12,999,999.50	8,703,879
01/08/2021	AAP	347,332	Indirect	COM	$9.21	$3,198,927.72	7,132,790
01/08/2021	AAP	152,668	Indirect	COM	$10.21	$1,558,740.28	7,285,458
01/08/2021	AAP	50,000	Indirect	COM	$7.60	$380,000.00	7,335,458
01/07/2021	AAP	500,000	Indirect	COM	$8.13	$4,065,000.00	6,785,458
07/09/2020	AAP	3,200,000	Indirect	COM	$4.25	$13,600,000.00	6,285,458

Trans. Date	Trans. Type	Shares	Ownership Type	Issue Type	Price	Trans. Value	Total Shares Owned
02/19/2025	AAP	5,000,000	Indirect	COM	$4.03	$20,150,000.00	11,833,539
01/11/2024	AAP	3,410,713	Indirect	COM	$5.53	$18,861,242.89	6,833,539
03/23/2021	AAP	2,608,695	Indirect	COM	$5.75	$14,999,996.25	13,412,552
07/25/2019	AAP	2,822,581	Indirect	COM	$4.65	$13,125,001.65	6,749,803
01/30/2018	AAP	1,000,000	Indirect	COM	$16.00	$16,000,000.00	3,907,222
01/30/2018	AAP	20,000	Indirect	COM	$27.33	$546,520.00	3,927,222

Trans. Date	Trans. Type	Shares	Ownership Type	Issue Type	Price	Trans. Value	Total Shares Owned
08/12/2024	AAP	1,250,000	Indirect	COM	$4.00	$5,000,000.00	12,531,103
11/23/2020	AAP	500,000	Indirect	COM	$12.85	$6,425,000.00	6,933,277
08/12/2019	AAP	425,531	Indirect	COM	$23.50	$9,999,978.50	6,433,277
06/12/2018	AAP	1,333,333	Indirect	COM	$15.00	$19,999,995.00	4,703,398
06/08/2018	AAP	50,000	Indirect	COM	$15.22	$761,000.00	3,370,065

Trans. Date	Trans. Type	Shares	Ownership Type	Issue Type	Price	Trans. Value	Total Shares Owned
12/29/2023	AAP	115,774	Indirect	COM	$7.24	$838,203.76	7,099,182
12/28/2023	AAP	126,116	Indirect	COM	$7.08	$892,901.28	6,983,408
12/27/2023	AAP	79,726	Indirect	COM	$7.20	$574,027.20	6,857,292
12/26/2023	AAP	54,652	Indirect	COM	$6.49	$354,691.48	6,777,566
12/22/2023	AAP	250,000	Indirect	COM	$6.67	$1,667,500.00	6,722,914
12/21/2023	AAP	200,000	Indirect	COM	$6.17	$1,234,000.00	6,472,914
12/19/2023	AAP	277,008	Indirect	COM	$5.36	$1,484,762.88	6,272,914
12/18/2023	AAP	456,923	Indirect	COM	$5.41	$2,471,953.43	5,995,906
12/15/2023	AAP	500,000	Indirect	COM	$5.97	$2,985,000.00	5,538,983
07/05/2022	AAP	1,428,571	Indirect	COM	$2.10	$2,999,999.10	5,038,983
06/19/2018	AAP	1,000,000	Indirect	COM	$15.00	$15,000,000.00	3,410,412

Trans. Date	Trans. Type	Shares	Ownership Type	Issue Type	Price	Trans. Value	Total Shares Owned
09/28/2023	AAP	250,000	Indirect	COM	$20.00	$5,000,000.00	3,074,542
09/26/2023	AAP	30,511	Indirect	COM	$13.92	$424,713.12	2,421,659
09/26/2023	AAP	37,911	Indirect	COM	$11.05	$418,916.55	2,270,473
09/26/2023	AAP	42,838	Indirect	COM	$12.84	$550,039.92	2,391,148
09/26/2023	AAP	5,703	Indirect	COM	$7.65	$43,627.95	2,213,456
09/26/2023	AAP	13,687	Indirect	COM	$8.30	$113,602.10	2,227,143
09/26/2023	AAP	5,419	Indirect	COM	$9.52	$51,588.88	2,232,562
09/26/2023	AAP	77,837	Indirect	COM	$11.81	$919,254.97	2,348,310
09/26/2023	AAP	3,326	Indirect	COM	$14.61	$48,592.86	2,424,985
09/26/2023	AAP	36,939	Indirect	COM	$21.00	$775,719.00	2,824,542
09/26/2023	AAP	88,685	Indirect	COM	$19.11	$1,694,770.35	2,669,607
09/26/2023	AAP	117,996	Indirect	COM	$20.03	$2,363,459.88	2,787,603
09/26/2023	AAP	27,769	Indirect	COM	$16.00	$444,304.00	2,452,754
09/26/2023	AAP	75,477	Indirect	COM	$17.28	$1,304,242.56	2,528,231
09/26/2023	AAP	52,691	Indirect	COM	$18.24	$961,083.84	2,580,922
06/06/2023	AAP	200	Indirect	COM	$5.93	$1,186.00	2,207,753
06/05/2023	AAP	78,468	Indirect	COM	$5.98	$469,238.64	2,207,553
06/02/2023	AAP	64,630	Indirect	COM	$5.93	$383,255.90	2,129,085
06/01/2023	AAP	7,500	Indirect	COM	$5.59	$41,925.00	2,064,455
05/31/2023	AAP	10,000	Indirect	COM	$5.28	$52,800.00	2,056,955
05/30/2023	AAP	17,500	Indirect	COM	$5.34	$93,450.00	2,046,955
05/23/2023	AAP	27,500	Indirect	COM	$5.45	$149,875.00	1,944,455
05/22/2023	AAP	27,300	Indirect	COM	$5.12	$139,776.00	1,916,955
05/19/2023	AAP	25,200	Indirect	COM	$4.62	$116,424.00	1,889,655

Trans. Date	Trans. Type	Shares	Ownership Type	Issue Type	Price	Trans. Value	Total Shares Owned
04/18/2022	AAP	157,515	Indirect	COM	$22.22	$3,499,983.30	5,321,032
10/25/2021	AAP	1,200,000	Indirect	COM	$19.80	$23,760,000.00	5,163,517
04/08/2021	AAP	304,136	Indirect	COM	$16.44	$4,999,995.84	3,963,517
04/17/2020	AAP	1,071,428	Indirect	COM	$14.00	$14,999,992.00	3,659,381
07/20/2018	AAP	400,000	Indirect	COM	$17.00	$6,800,000.00	2,280,305

Trans. Date	Trans. Type	Shares	Ownership Type	Issue Type	Price	Trans. Value	Total Shares Owned
12/08/2021	AAP	200,000	Indirect	COM	$5.36	$1,072,000.00	9,111,151
06/09/2021	AAP	5,500,000	Indirect	COM	$10.00	$55,000,000.00	5,997,038
05/24/2021	AAP	7,063	Direct	COM	$10.05	$70,983.15	497,038

Trans. Date	Trans. Type	Shares	Ownership Type	Issue Type	Price	Trans. Value	Total Shares Owned
10/12/2021	DDS	7,306	Indirect	COM	$13.40	$97,900.40	2,487,019
10/11/2021	DDS	12,475	Indirect	COM	$12.03	$150,074.25	2,503,676
10/11/2021	DDS	9,351	Indirect	COM	$13.15	$122,965.65	2,494,325
10/08/2021	DDS	5,038	Indirect	COM	$12.90	$64,990.20	2,518,613
10/08/2021	DDS	2,462	Indirect	COM	$13.66	$33,630.92	2,516,151
10/07/2021	DDS	13,082	Indirect	COM	$14.80	$193,613.60	2,523,937
10/07/2021	DDS	286	Indirect	COM	$15.05	$4,304.30	2,523,651
04/27/2021	AAP	550,000	Indirect	COM	$17.00	$9,350,000.00	2,537,019

Trans. Date	Trans. Type	Shares	Ownership Type	Issue Type	Price	Trans. Value	Total Shares Owned
09/30/2021	DDS	137,495	Indirect	COM	$1.12	$153,994.40	13,262,375
09/29/2021	DDS	82,505	Indirect	COM	$1.16	$95,705.80	13,399,870
09/28/2021	DDS	40,603	Indirect	COM	$1.22	$49,535.66	13,482,375
09/27/2021	DDS	250,000	Indirect	COM	$1.23	$307,500.00	13,522,978
09/24/2021	DDS	250,000	Indirect	COM	$1.26	$315,000.00	13,772,978
09/23/2021	DDS	780,000	Indirect	COM	$1.27	$990,600.00	14,022,978
08/19/2021	DDS	350,352	Indirect	COM	$1.24	$434,436.48	14,802,978
08/18/2021	DDS	552,380	Indirect	COM	$1.29	$712,570.20	15,153,330
08/17/2021	DDS	879,092	Indirect	COM	$1.35	$1,186,774.20	15,705,710
03/19/2020	AAP	500,000	Indirect	COM	$2.10	$1,050,000.00	16,584,802
02/11/2020	AAP	4,563,700	Indirect	COM	$3.50	$15,972,950.00	16,084,802
05/21/2019	AAP	4,000,000	Indirect	COM	$4.00	$16,000,000.00	11,521,102

Trans. Date	Trans. Type	Shares	Ownership Type	Issue Type	Price	Trans. Value	Total Shares Owned
08/16/2021	DDS	250,000	Indirect	COM	$1.74	$435,000.00	4,935,057
08/13/2021	DDS	250,000	Indirect	COM	$1.84	$460,000.00	5,185,057
08/12/2021	DDS	338,897	Indirect	COM	$2.23	$755,740.31	5,435,057
05/06/2021	DDS	1,000,000	Indirect	COM	$3.67	$3,670,000.00	5,773,954
01/28/2021	AAP	4,219,409	Indirect	COM	$2.37	$9,999,999.33	27,095,819

Trans. Date	Trans. Type	Shares	Ownership Type	Issue Type	Price	Trans. Value	Total Shares Owned
01/22/2021	DDS	33,849	Indirect	COM	$8.95	$302,948.55	1,800,000
01/22/2021	DDS	285,151	Indirect	COM	$8.16	$2,326,832.16	1,833,849
01/21/2021	DDS	95,000	Indirect	COM	$7.38	$701,100.00	2,120,000
01/20/2021	DDS	185,000	Indirect	COM	$7.43	$1,374,550.00	2,215,000

Trans. Date	Trans. Type	Shares	Ownership Type	Issue Type	Price	Trans. Value	Total Shares Owned
01/22/2021	DDS	550,000	Indirect	COM	$1.48	$814,000.00	2,660,542
01/21/2021	DDS	674,352	Indirect	COM	$1.68	$1,132,911.36	3,210,542
01/20/2021	DDS	325,648	Indirect	COM	$1.80	$586,166.40	3,884,894
06/27/2019	AAP	1,000,000	Indirect	COM	$3.00	$3,000,000.00	4,210,542
12/24/2018	AAP	400,000	Indirect	COM	$2.70	$1,080,000.00	3,210,541
02/16/2018	AAP	1,000,000	Indirect	COM	$5.00	$5,000,000.00	2,800,541
02/14/2018	AAP	10,000	Indirect	COM	$5.00	$50,000.00	2,810,541

Trans. Date	Trans. Type	Shares	Ownership Type	Issue Type	Price	Trans. Value	Total Shares Owned
10/03/2018	AAP	30,000	Indirect	COM	$12.69	$380,700.00	20,724,424
09/24/2018	AAP	20,000	Indirect	COM	$12.45	$249,000.00	20,694,424
09/21/2018	AAP	50,000	Indirect	COM	$12.53	$626,500.00	20,674,424
09/13/2018	AAP	100,000	Indirect	COM	$11.74	$1,174,000.00	20,624,424
09/12/2018	AAP	500,000	Indirect	COM	$12.00	$6,001,500.00	20,524,424
03/05/2018	AAP	335,827	Indirect	COM	$13.56	$4,553,814.12	18,424,424
03/02/2018	AAP	100,000	Indirect	COM	$13.90	$1,389,500.00	18,088,597
03/01/2018	AAP	100,000	Indirect	COM	$13.69	$1,369,000.00	17,988,597
07/13/2017	AAP	1,500,000	Indirect	COM	$12.25	$18,375,000.00	17,888,597
12/30/2016	AAP	94,750	Indirect	COM	$4.96	$470,054.75	16,293,847
12/29/2016	AAP	94,750	Indirect	COM	$4.85	$459,916.50	16,293,847
12/28/2016	AAP	47,375	Indirect	COM	$4.91	$232,706.00	16,199,097
12/23/2016	AAP	47,375	Indirect	COM	$4.72	$223,467.88	16,113,822
12/23/2016	AAP	37,900	Indirect	COM	$4.92	$186,581.70	16,151,722
12/22/2016	AAP	189,500	Indirect	COM	$4.51	$854,834.50	16,066,447
08/25/2016	DDS	1,100,000	Indirect	COM	$6.81	$7,491,000.00	14,139,444
10/07/2015	AAP	50,000	Indirect	COM	$6.27	$313,500.00	15,239,444
10/06/2015	AAP	86,000	Indirect	COM	$6.65	$571,900.00	15,025,444
10/06/2015	AAP	14,000	Indirect	COM	$6.47	$90,580.00	15,182,444
10/06/2015	AAP	86,000	Indirect	COM	$6.47	$556,420.00	15,111
10/06/2015	AAP	7,000	Indirect	COM	$6.34	$44,380.00	15,189,444
10/06/2015	AAP	43,000	Indirect	COM	$6.34	$272,620.00	15,154,444
10/06/2015	AAP	14,000	Indirect	COM	$6.65	$93,100.00	15,168,444
10/05/2015	AAP	215,000	Indirect	COM	$6.85	$1,472,750.00	14,654,444
10/05/2015	AAP	35,000	Indirect	COM	$6.76	$236,600.00	14,939,444

Trans. Date	Trans. Type	Shares	Ownership Type	Issue Type	Price	Trans. Value	Total Shares Owned
05/14/2012	AAP	59,500	Indirect	COM	$7.38	$439,282.55	2,862,560
05/11/2012	AAP	25,000	Indirect	COM	$6.35	$158,800.00	2,803,060
05/11/2012	AAP	145,000	Indirect	COM	$6.35	$921,040.00	2,778,060
05/10/2012	AAP	15,000	Indirect	COM	$4.82	$72,300.00	2,633,060
05/10/2012	AAP	310,000	Indirect	COM	$4.82	$1,493,797.00	2,618,060
08/19/2011	AAP	30,300	Indirect	COM	$7.50	$227,250.00	2,308,060
08/19/2011	AAP	400,000	Indirect	COM	$5.00	$2,000,000.00	1,982,460
08/19/2011	AAP	200,000	Indirect	COM	$5.00	$1,000,000.00	2,277,760
08/19/2011	AAP	95,300	Indirect	COM	$7.50	$714,750.00	2,077,760
08/12/2011	AAP	800	Indirect	COM	$7.50	$6,000.00	1,582,460
08/09/2011	AAP	3,800	Indirect	COM	$7.50	$28,500.00	1,581,660
08/08/2011	AAP	100	Indirect	COM	$7.50	$750.00	1,577,860
08/08/2011	AAP	4,600	Indirect	COM	$7.50	$34,500.00	1,577,760
08/05/2011	AAP	15,100	Indirect	COM	$7.50	$113,250.00	1,573,160
03/16/2011	AAP	60,000	Indirect	COM	$5.22	$313,200.00	1,558,060
03/16/2011	AAP	26,500	Indirect	COM	$5.19	$137,535.00	1,498,060
03/07/2011	AAP	30,000	Indirect	COM	$6.47	$194,100.00	1,471,560
03/01/2011	AAP	20,000	Indirect	COM	$4.62	$92,400.00	1,441,560
03/01/2011	AAP	30,000	Indirect	COM	$4.62	$138,600.00	1,421,560
02/28/2011	AAP	88,273	Indirect	COM	$4.46	$393,697.58	1,391,560
02/25/2011	AAP	10,000	Indirect	COM	$4.49	$44,900.00	1,303,287
02/25/2011	AAP	38,922	Indirect	COM	$4.49	$174,759.78	1,293,287
02/24/2011	AAP	110,000	Indirect	COM	$4.36	$479,600.00	1,254,365

Transaction Type Key
First letter: A = Acquired, D = Disposed
Second letter:
A = Grant, award or other acquisition pursuant to Rule 16b-3(d) C = Conversion of derivative security | D = Disposition to the issuer of issuer equity securities pursuant to Rule 16b-3(e) | E = Expiration of short derivative position | F = Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3. | G = Gift | H = Expiration (or cancellation) of long derivative position with value received | I = Discretionary transaction in accordance with Rule 16b-3(f) | J = Other | L = Small acquisition under Rule 16a-6 | M = Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 | O = Exercise of out-of-the-money derivative security | P = Open market or private purchase | S = Open market or private sale | U = Disposition pursuant to a tender of shares in a change of control transaction | W = Acquisition or disposition by will or the laws of descent and distribution | X = Exercise of in-the-money or at-the-money derivative security | Z = Deposit into or withdrawal from voting trust

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