| Transactions | |||
| All | Buy | Sell | Option Exercise |
Filer's Name |
Relationship/ Title |
Trans. Date |
Trans. Type |
Ownership Type |
Security Type |
Shares |
Price |
Trans. Value |
Total Shares Owned |
| Vultaggio Vincent | PAO and PFO | 02/10/2026 | DS | Direct | COM | 6,894 | $2.42 | $16,699.34 | 146,506 |
| Eastland Julia Marie | CEO & President | 02/09/2026 | DS | Direct | COM | 889 | $2.39 | $2,127.29 | 79,133 |
| Bruns Ingmar | Chief Medical Officer | 02/09/2026 | DS | Direct | COM | 335 | $2.39 | $801.62 | 33,332 |
| Vultaggio Vincent | PAO and PFO | 02/09/2026 | DS | Direct | COM | 3,379 | $2.39 | $8,085.61 | 153,400 |
| Eastland Julia Marie | CEO & President | 02/06/2026 | DS | Direct | COM | 7,866 | $2.43 | $19,112.02 | 80,022 |
| Bruns Ingmar | Chief Medical Officer | 02/06/2026 | DS | Direct | COM | 2,962 | $2.43 | $7,196.77 | 33,667 |
| Vultaggio Vincent | PAO and PFO | 02/06/2026 | DS | Direct | COM | 29,951 | $2.43 | $72,771.94 | 156,779 |
| Vultaggio Vincent | PAO and PFO | 02/03/2026 | DS | Direct | COM | 556 | $2.52 | $1,398.34 | 186,730 |
| Vultaggio Vincent | PAO and PFO | 02/02/2026 | DS | Direct | COM | 2,540 | $2.55 | $6,477.00 | 187,286 |
| Walters Group | Other | 12/31/2025 | AP | Direct | COM | 6,459,973 | $1.20 | $7,751,967.60 | 13,509,973 |
| Matrix Capital Management Company, Lp | Other | 12/15/2025 | DS | Indirect | COM | 7,500,000 | $1.33 | $9,975,000.00 | 6,459,973 |
| Myers Scott Dunseth | Director | 06/17/2025 | AA | Direct | COM | 57,603 | $0.00 | $0.00 | 338,795 |
| Kariuki Enoch | Director | 06/17/2025 | AA | Direct | COM | 57,603 | $0.00 | $0.00 | 137,365 |
| Johnson David Michael | Director | 06/17/2025 | AA | Direct | COM | 57,603 | $0.00 | $0.00 | 250,421 |
| Skvarka Jan | Director | 06/17/2025 | AA | Direct | COM | 57,603 | $0.00 | $0.00 | 207,154 |
| Walker Luke Nathaniel | Director | 06/17/2025 | AA | Direct | COM | 57,603 | $0.00 | $0.00 | 144,284 |
| Myers Scott Dunseth | Director | 04/30/2025 | AP | Direct | COM | 21,000 | $1.40 | $29,372.70 | 281,192 |
| Bruns Ingmar | Chief Medical Officer | 02/06/2025 | AP | Direct | COM | 20,000 | $2.28 | $45,656.00 | 36,629 |
| Eastland Julia Marie | CEO & President | 02/03/2025 | AA | Direct | COM | 59,388 | $0.00 | $0.00 | 87,888 |
| Bruns Ingmar | Chief Medical Officer | 02/03/2025 | AA | Direct | COM | 16,629 | $0.00 | $0.00 | 16,629 |
| Paul Andrea | Chief Legal Officer | 02/03/2025 | DS | Direct | COM | 13,230 | $1.71 | $22,643.15 | 1,070,784 |
| Paul Andrea | Chief Legal Officer | 02/03/2025 | AA | Direct | COM | 934,041 | $0.00 | $0.00 | 1,084,014 |
| Lackner Mark | Chief Scientific Officer | 02/03/2025 | DS | Direct | COM | 14,368 | $1.71 | $24,590.83 | 512,856 |
| Lackner Mark | Chief Scientific Officer | 02/03/2025 | AA | Direct | COM | 335,907 | $0.00 | $0.00 | 527,224 |
| Vultaggio Vincent | PAO and Interim PFO | 02/03/2025 | DS | Direct | COM | 2,615 | $1.71 | $4,475.57 | 189,826 |
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Transaction Type Key First letter: A = Acquired, D = Disposed Second letter: A = Grant, award or other acquisition pursuant to Rule 16b-3(d) C = Conversion of derivative security | D = Disposition to the issuer of issuer equity securities pursuant to Rule 16b-3(e) | E = Expiration of short derivative position | F = Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3. | G = Gift | H = Expiration (or cancellation) of long derivative position with value received | I = Discretionary transaction in accordance with Rule 16b-3(f) | J = Other | L = Small acquisition under Rule 16a-6 | M = Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 | O = Exercise of out-of-the-money derivative security | P = Open market or private purchase | S = Open market or private sale | U = Disposition pursuant to a tender of shares in a change of control transaction | W = Acquisition or disposition by will or the laws of descent and distribution | X = Exercise of in-the-money or at-the-money derivative security | Z = Deposit into or withdrawal from voting trust |
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