QUODD

Insider Transactions last 24 months for Septerna, Inc. - NSDQ: SEPN

Transactions
All	Buy	Sell	Option Exercise

Filer's Name	Relationship/ Title	Trans. Date	Trans. Type	Ownership Type	Security Type	Shares	Price	Trans. Value	Total Shares Owned
Klein Uwe	SVP, Biological Sciences	08/18/2025	AM	Direct	COM	7,621	$6.81	$51,899.01	23,008
Klein Uwe	SVP, Biological Sciences	08/18/2025	AM	Direct	COM	4,935	$2.76	$13,620.60	15,387
Klein Uwe	SVP, Biological Sciences	08/18/2025	AM	Direct	COM	10,452	$2.76	$28,847.52	10,452
Finer Jeffrey	CEO and President	04/03/2025	AM	Direct	COM	5,000	$2.76	$13,800.00	826,907
Finer Jeffrey	CEO and President	04/02/2025	AM	Direct	COM	50,000	$2.76	$138,000.00	821,907
Ezekowitz Alan	Director	03/07/2025	AP	Direct	COM	13,319	$6.93	$92,270.04	117,420
Ezekowitz Alan	Director	03/06/2025	AP	Direct	COM	41,355	$6.00	$248,130.00	104,101
Ezekowitz Alan	Director	03/05/2025	AP	Direct	COM	37,835	$5.82	$220,260.24	62,746
Ezekowitz Alan	Director	03/04/2025	AP	Direct	COM	7,491	$6.35	$47,543.88	24,911
Third Rock Ventures Vi, L.P.	Other	02/24/2025	AP	Direct	COM	18,861	$6.00	$113,147.14	4,211,659
Labrucherie Gil M	Chief Financial Officer	02/21/2025	AP	Indirect	COM	5,000	$5.85	$29,250.00	30,000
Third Rock Ventures Vi, L.P.	Other	02/21/2025	AP	Direct	COM	427,668	$5.94	$2,540,347.92	4,192,798
Labrucherie Gil M	Chief Financial Officer	02/20/2025	AP	Indirect	COM	14,500	$5.88	$85,233.90	25,000
Third Rock Ventures Vi, L.P.	Other	02/20/2025	AP	Direct	COM	612,674	$5.92	$3,627,030.08	3,765,130
Labrucherie Gil M	Chief Financial Officer	02/19/2025	AP	Indirect	COM	10,500	$5.51	$57,813.00	10,500
Third Rock Ventures V, L.P.	Other	10/28/2024	AP	Indirect	COM	279,500	$18.00	$5,031,000.00	3,152,456
Third Rock Ventures V, L.P.	Other	10/28/2024	AP	Direct	COM	370,500	$18.00	$6,669,000.00	6,215,591
Third Rock Ventures V, L.P.	Other	10/28/2024	AC	Indirect	COM	2,872,956	$0.00	$0.00	2,872,956
Third Rock Ventures V, L.P.	Other	10/28/2024	AC	Direct	COM	4,790,773	$0.00	$0.00	5,845,091
Ra Capital Management, L.P.	Director	10/28/2024	AP	Indirect	COM	341,600	$18.00	$6,148,800.00	1,471,943
Ra Capital Management, L.P.	Director	10/28/2024	AP	Indirect	COM	3,828,400	$18.00	$68,911,200.00	5,523,915
Ra Capital Management, L.P.	Director	10/28/2024	AC	Indirect	COM	1,130,343	$0.00	$0.00	1,130,343
Ra Capital Management, L.P.	Director	10/28/2024	AC	Indirect	COM	1,695,515	$0.00	$0.00	1,695,515

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Transaction Type Key First letter: A = Acquired, D = Disposed Second letter: A = Grant, award or other acquisition pursuant to Rule 16b-3(d) C = Conversion of derivative security \| D = Disposition to the issuer of issuer equity securities pursuant to Rule 16b-3(e) \| E = Expiration of short derivative position \| F = Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3. \| G = Gift \| H = Expiration (or cancellation) of long derivative position with value received \| I = Discretionary transaction in accordance with Rule 16b-3(f) \| J = Other \| L = Small acquisition under Rule 16a-6 \| M = Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 \| O = Exercise of out-of-the-money derivative security \| P = Open market or private purchase \| S = Open market or private sale \| U = Disposition pursuant to a tender of shares in a change of control transaction \| W = Acquisition or disposition by will or the laws of descent and distribution \| X = Exercise of in-the-money or at-the-money derivative security \| Z = Deposit into or withdrawal from voting trust		Send to Excel

Transaction Type Key
First letter: A = Acquired, D = Disposed
Second letter:
A = Grant, award or other acquisition pursuant to Rule 16b-3(d) C = Conversion of derivative security | D = Disposition to the issuer of issuer equity securities pursuant to Rule 16b-3(e) | E = Expiration of short derivative position | F = Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3. | G = Gift | H = Expiration (or cancellation) of long derivative position with value received | I = Discretionary transaction in accordance with Rule 16b-3(f) | J = Other | L = Small acquisition under Rule 16a-6 | M = Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 | O = Exercise of out-of-the-money derivative security | P = Open market or private purchase | S = Open market or private sale | U = Disposition pursuant to a tender of shares in a change of control transaction | W = Acquisition or disposition by will or the laws of descent and distribution | X = Exercise of in-the-money or at-the-money derivative security | Z = Deposit into or withdrawal from voting trust

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