| Transactions | |||
| All | Buy | Sell | Option Exercise |
Filer's Name |
Relationship/ Title |
Trans. Date |
Trans. Type |
Ownership Type |
Security Type |
Shares |
Price |
Trans. Value |
Total Shares Owned |
| Suvretta Capital Management, Llc | Director | 02/06/2026 | AP | Indirect | COM | 19,338 | $36.55 | $706,803.90 | 520,453 |
| Suvretta Capital Management, Llc | Director | 02/06/2026 | AP | Indirect | COM | 11,183 | $35.97 | $402,252.51 | 501,115 |
| Suvretta Capital Management, Llc | Director | 02/05/2026 | AP | Indirect | COM | 16,563 | $39.80 | $659,207.40 | 489,932 |
| Suvretta Capital Management, Llc | Director | 02/05/2026 | AP | Indirect | COM | 17,835 | $38.67 | $689,679.45 | 473,369 |
| Suvretta Capital Management, Llc | Director | 02/05/2026 | AP | Indirect | COM | 38,771 | $37.63 | $1,458,952.73 | 455,534 |
| Suvretta Capital Management, Llc | Director | 02/05/2026 | AP | Indirect | COM | 19,199 | $36.93 | $709,019.07 | 416,763 |
| Suvretta Capital Management, Llc | Director | 02/05/2026 | AP | Indirect | COM | 3,832 | $36.07 | $138,220.24 | 397,564 |
| Waldman Reid Alexander | Chief Executive Officer | 02/05/2026 | AC | Direct | COM | 1,437 | $0.00 | $0.00 | 234,872 |
| Durso Timothy August | Chief Technical Officer | 02/05/2026 | AC | Direct | COM | 1,473 | $0.00 | $0.00 | 118,190 |
| Enright Patrick G | Director | 02/05/2026 | AP | Indirect | COM | 882,353 | $17.00 | $15,000,001.00 | 2,053,474 |
| Enright Patrick G | Director | 02/05/2026 | AP | Indirect | COM | 192,647 | $17.00 | $3,274,999.00 | 2,600,399 |
| Enright Patrick G | Director | 02/05/2026 | AC | Indirect | COM | 1,171,121 | $0.00 | $0.00 | 1,171,121 |
| Enright Patrick G | Director | 02/05/2026 | AC | Indirect | COM | 1,171,121 | $0.00 | $0.00 | 2,407,752 |
| Enright Patrick G | Director | 02/05/2026 | AC | Indirect | COM | 1,236,631 | $0.00 | $0.00 | 1,236,631 |
| Longitude Capital Partners V, Llc | Other | 02/05/2026 | AP | Indirect | COM | 882,353 | $17.00 | $15,000,001.00 | 2,053,474 |
| Longitude Capital Partners V, Llc | Other | 02/05/2026 | AP | Indirect | COM | 192,647 | $17.00 | $3,274,999.00 | 2,600,399 |
| Longitude Capital Partners V, Llc | Other | 02/05/2026 | AC | Indirect | COM | 1,171,121 | $0.00 | $0.00 | 1,171,121 |
| Longitude Capital Partners V, Llc | Other | 02/05/2026 | AC | Indirect | COM | 1,171,121 | $0.00 | $0.00 | 2,407,752 |
| Longitude Capital Partners V, Llc | Other | 02/05/2026 | AC | Indirect | COM | 1,236,631 | $0.00 | $0.00 | 1,236,631 |
| Childs John W | Director | 02/05/2026 | AP | Indirect | COM | 294,117 | $17.00 | $4,999,989.00 | 2,202,006 |
| Childs John W | Director | 02/05/2026 | AC | Indirect | COM | 520,758 | $0.00 | $0.00 | 1,907,889 |
| Childs John W | Director | 02/05/2026 | AC | Indirect | COM | 906,862 | $0.00 | $0.00 | 1,387,131 |
| Childs John W | Director | 02/05/2026 | AC | Indirect | COM | 480,269 | $0.00 | $0.00 | 480,269 |
| Coric Vlad | Director | 02/05/2026 | AP | Indirect | COM | 58,823 | $17.00 | $999,991.00 | 319,398 |
| Coric Vlad | Director | 02/05/2026 | AP | Indirect | COM | 58,823 | $17.00 | $999,991.00 | 319,398 |
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Transaction Type Key First letter: A = Acquired, D = Disposed Second letter: A = Grant, award or other acquisition pursuant to Rule 16b-3(d) C = Conversion of derivative security | D = Disposition to the issuer of issuer equity securities pursuant to Rule 16b-3(e) | E = Expiration of short derivative position | F = Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3. | G = Gift | H = Expiration (or cancellation) of long derivative position with value received | I = Discretionary transaction in accordance with Rule 16b-3(f) | J = Other | L = Small acquisition under Rule 16a-6 | M = Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 | O = Exercise of out-of-the-money derivative security | P = Open market or private purchase | S = Open market or private sale | U = Disposition pursuant to a tender of shares in a change of control transaction | W = Acquisition or disposition by will or the laws of descent and distribution | X = Exercise of in-the-money or at-the-money derivative security | Z = Deposit into or withdrawal from voting trust |
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