| Transactions | |||
| All | Buy | Sell | Option Exercise |
Filer's Name |
Relationship/ Title |
Trans. Date |
Trans. Type |
Ownership Type |
Security Type |
Shares |
Price |
Trans. Value |
Total Shares Owned |
| Sherman Jeffrey W | Director | 02/27/2026 | AP | Direct | COM | 5,000 | $5.00 | $25,000.00 | 5,000 |
| Thomas Frank E | Director | 02/27/2026 | AP | Direct | COM | 5,000 | $5.00 | $25,000.00 | 7,000 |
| Hamilton Thomas Edward | Director | 02/27/2026 | AP | Direct | COM | 100,000 | $5.00 | $500,000.00 | 664,798 |
| Flynn James E | Director | 02/27/2026 | AP | Indirect | COM | 2,000,000 | $5.00 | $10,000,000.00 | 6,207,982 |
| Flynn James E | Director | 02/27/2026 | AP | Indirect | COM | 831,978 | $5.00 | $4,159,890.00 | 8,153,107 |
| Flynn James E | Director | 02/27/2026 | AP | Indirect | COM | 1,084,012 | $5.00 | $5,420,060.00 | 10,622,957 |
| Flynn James E | Director | 02/27/2026 | AP | Indirect | COM | 1,084,010 | $5.00 | $5,420,050.00 | 10,622,928 |
| Celano Michael | Chief Financial Officer | 01/26/2026 | AA | Direct | COM | 37,604 | $0.00 | $0.00 | 215,785 |
| Ben-Maimon Carole | President and CEO | 01/26/2026 | AA | Direct | COM | 100,100 | $0.00 | $0.00 | 368,276 |
| Clayton Russell | Chief Medical Officer | 01/26/2026 | AA | Direct | COM | 25,637 | $0.00 | $0.00 | 71,443 |
| Shankar Gopi | Chief Development Officer | 01/26/2026 | AA | Direct | COM | 25,637 | $0.00 | $0.00 | 76,443 |
| Flynn James E | Director | 07/31/2025 | AP | Indirect | COM | 2,599,932 | $3.20 | $8,319,782.40 | 7,321,129 |
| Flynn James E | Director | 07/31/2025 | AP | Indirect | COM | 3,387,539 | $3.20 | $10,840,124.80 | 9,538,945 |
| Flynn James E | Director | 07/31/2025 | AP | Indirect | COM | 3,387,529 | $3.20 | $10,840,092.80 | 9,538,918 |
| Celano Michael | Chief Financial Officer | 01/22/2025 | AA | Direct | COM | 34,185 | $0.00 | $0.00 | 178,181 |
| Ben-Maimon Carole | President and CEO | 01/22/2025 | AA | Direct | COM | 91,000 | $0.00 | $0.00 | 387,208 |
| Clayton Russell | Chief Medical Officer | 01/22/2025 | AA | Direct | COM | 23,306 | $0.00 | $0.00 | 45,806 |
| Shankar Gopi | Chief Development Officer | 01/22/2025 | AA | Direct | COM | 23,306 | $0.00 | $0.00 | 50,806 |
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Transaction Type Key First letter: A = Acquired, D = Disposed Second letter: A = Grant, award or other acquisition pursuant to Rule 16b-3(d) C = Conversion of derivative security | D = Disposition to the issuer of issuer equity securities pursuant to Rule 16b-3(e) | E = Expiration of short derivative position | F = Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3. | G = Gift | H = Expiration (or cancellation) of long derivative position with value received | I = Discretionary transaction in accordance with Rule 16b-3(f) | J = Other | L = Small acquisition under Rule 16a-6 | M = Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 | O = Exercise of out-of-the-money derivative security | P = Open market or private purchase | S = Open market or private sale | U = Disposition pursuant to a tender of shares in a change of control transaction | W = Acquisition or disposition by will or the laws of descent and distribution | X = Exercise of in-the-money or at-the-money derivative security | Z = Deposit into or withdrawal from voting trust |
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