| Transactions | |||
| All | Buy | Sell | Option Exercise |
Filer's Name |
Relationship/ Title |
Trans. Date |
Trans. Type |
Ownership Type |
Security Type |
Shares |
Price |
Trans. Value |
Total Shares Owned |
| Opaleye Management Inc. | Other | 03/04/2026 | DS | Indirect | COM | 4,263 | $39.67 | $169,122.16 | 59,428 |
| Opaleye Management Inc. | Other | 03/04/2026 | DS | Indirect | COM | 134,000 | $39.67 | $5,316,061.40 | 3,622,000 |
| Opaleye Management Inc. | Other | 03/03/2026 | DS | Indirect | COM | 1,309 | $39.15 | $51,250.49 | 63,691 |
| Opaleye Management Inc. | Other | 03/03/2026 | DS | Indirect | COM | 59,000 | $39.15 | $2,309,991.60 | 3,756,000 |
| Opaleye Management Inc. | Other | 02/27/2026 | DS | Indirect | COM | 5,000 | $54.18 | $270,900.00 | 65,000 |
| Opaleye Management Inc. | Other | 01/06/2026 | DS | Indirect | COM | 20,000 | $53.35 | $1,066,914.00 | 70,000 |
| Baum Mark L | CHIEF EXECUTIVE OFFICER | 12/12/2025 | DF | Direct | COM | 79,994 | $47.06 | $3,764,517.64 | 2,986,130 |
| Baum Mark L | CHIEF EXECUTIVE OFFICER | 12/12/2025 | AM | Direct | COM | 180,000 | $3.95 | $711,000.00 | 3,066,124 |
| Boll Andrew R. | PRESIDENT AND CFO | 12/12/2025 | DF | Direct | COM | 26,665 | $47.06 | $1,254,854.90 | 811,179 |
| Boll Andrew R. | PRESIDENT AND CFO | 12/12/2025 | AM | Direct | COM | 60,000 | $3.95 | $237,000.00 | 837,844 |
| Baum Mark L | CHIEF EXECUTIVE OFFICER | 07/21/2025 | DF | Direct | COM | 313,338 | $37.08 | $11,618,573.04 | 2,886,124 |
| Baum Mark L | CHIEF EXECUTIVE OFFICER | 07/21/2025 | AM | Direct | COM | 600,000 | $7.87 | $4,722,000.00 | 3,199,462 |
| Opaleye Management Inc. | Other | 06/10/2025 | DS | Indirect | COM | 15,000 | $30.80 | $462,033.00 | 90,000 |
| Opaleye Management Inc. | Other | 06/09/2025 | DS | Indirect | COM | 15,204 | $30.37 | $461,794.13 | 105,000 |
| Opaleye Management Inc. | Other | 06/04/2025 | DS | Indirect | COM | 1,796 | $30.02 | $53,907.48 | 120,204 |
| Opaleye Management Inc. | Other | 06/03/2025 | DS | Indirect | COM | 3,000 | $30.04 | $90,116.10 | 122,000 |
| Opaleye Management Inc. | Other | 05/13/2025 | DS | Indirect | COM | 5,000 | $26.59 | $132,945.00 | 125,000 |
| Opaleye Management Inc. | Other | 05/12/2025 | DS | Indirect | COM | 10,000 | $25.90 | $258,959.00 | 130,000 |
| Baum Mark L | Chief Executive Officer | 04/07/2025 | DF | Direct | COM | 300,363 | $23.09 | $6,935,381.67 | 2,599,462 |
| Saharek John P. | CEO & President, ImprimisRx | 04/07/2025 | DF | Direct | COM | 109,475 | $23.09 | $2,527,777.75 | 467,388 |
| Boll Andrew R. | Chief Financial Officer | 04/07/2025 | DF | Direct | COM | 136,745 | $23.09 | $3,157,442.05 | 777,844 |
| Baum Mark L | Chief Executive Officer | 04/03/2025 | AM | Direct | COM | 762,300 | $0.00 | $0.00 | 2,899,825 |
| Saharek John P. | CEO & President, ImprimisRx | 04/03/2025 | AM | Direct | COM | 277,200 | $0.00 | $0.00 | 576,863 |
| Boll Andrew R. | Chief Financial Officer | 04/03/2025 | AM | Direct | COM | 346,500 | $0.00 | $0.00 | 914,589 |
| Opaleye Management Inc. | Other | 03/18/2025 | DS | Indirect | COM | 5,000 | $29.64 | $148,200.00 | 145,000 |
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Transaction Type Key First letter: A = Acquired, D = Disposed Second letter: A = Grant, award or other acquisition pursuant to Rule 16b-3(d) C = Conversion of derivative security | D = Disposition to the issuer of issuer equity securities pursuant to Rule 16b-3(e) | E = Expiration of short derivative position | F = Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3. | G = Gift | H = Expiration (or cancellation) of long derivative position with value received | I = Discretionary transaction in accordance with Rule 16b-3(f) | J = Other | L = Small acquisition under Rule 16a-6 | M = Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 | O = Exercise of out-of-the-money derivative security | P = Open market or private purchase | S = Open market or private sale | U = Disposition pursuant to a tender of shares in a change of control transaction | W = Acquisition or disposition by will or the laws of descent and distribution | X = Exercise of in-the-money or at-the-money derivative security | Z = Deposit into or withdrawal from voting trust |
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