| Transactions | |||
| All | Buy | Sell | Option Exercise |
Filer's Name |
Relationship/ Title |
Trans. Date |
Trans. Type |
Ownership Type |
Security Type |
Shares |
Price |
Trans. Value |
Total Shares Owned |
| Valamehr Bahram | President and CEO | 01/15/2026 | AA | Direct | COM | 335,000 | $0.00 | $0.00 | 664,708 |
| Adawi Kamal | Chief Financial Officer | 01/15/2026 | AA | Direct | COM | 25,000 | $0.00 | $0.00 | 100,000 |
| Tahl Cindy | See Remarks | 01/15/2026 | AA | Direct | COM | 100,000 | $0.00 | $0.00 | 487,081 |
| Valamehr Bahram | President and CEO | 01/09/2026 | DS | Direct | COM | 5,190 | $1.07 | $5,557.45 | 329,708 |
| Tahl Cindy | See Remarks | 01/09/2026 | DS | Direct | COM | 10,589 | $1.06 | $11,275.17 | 387,081 |
| Adawi Kamal | Chief Financial Officer | 10/20/2025 | AA | Direct | COM | 75,000 | $0.00 | $0.00 | 75,000 |
| Valamehr Bahram | President and CEO | 08/04/2025 | DS | Direct | COM | 14,466 | $1.06 | $15,396.16 | 334,898 |
| Tahl Cindy | See Remarks | 08/04/2025 | DS | Direct | COM | 9,037 | $1.06 | $9,572.89 | 397,670 |
| Bressi Jerome Charles | See Remarks | 01/15/2025 | AA | Direct | COM | 65,000 | $0.00 | $0.00 | 335,203 |
| Tahl Cindy | See Remarks | 01/15/2025 | AA | Direct | COM | 70,000 | $0.00 | $0.00 | 406,707 |
| Valamehr Bahram | President and CEO | 01/10/2025 | DS | Direct | COM | 8,705 | $1.54 | $13,405.70 | 349,364 |
| Tahl Cindy | See Remarks | 01/10/2025 | DS | Direct | COM | 5,654 | $1.55 | $8,763.70 | 336,707 |
| Bressi Jerome Charles | See Remarks | 01/10/2025 | DS | Direct | COM | 5,980 | $1.55 | $9,269.00 | 270,203 |
| Redmile Group, Llc | Director | 12/20/2024 | AP | Indirect | COM | 397,964 | $1.68 | $668,579.52 | 12,884,277 |
| Redmile Group, Llc | Director | 12/20/2024 | DS | Indirect | COM | 341,633 | $1.68 | $573,943.44 | 12,486,313 |
| Redmile Group, Llc | Director | 12/20/2024 | AJ | Indirect | COM | 1,084,936 | $1.68 | $1,822,692.48 | 12,827,946 |
| Redmile Group, Llc | Director | 12/20/2024 | DJ | Indirect | COM | 1,084,936 | $1.68 | $1,822,692.48 | 11,743,010 |
| Redmile Group, Llc | Director | 12/12/2024 | AC | Indirect | COM | 30,110 | $0.00 | $0.00 | 12,827,946 |
| Xu Yuan | Director | 08/06/2024 | DS | Direct | COM | 633 | $4.23 | $2,677.59 | 8,669 |
| Tahl Cindy | General Counsel and Secretary | 07/29/2024 | AA | Direct | COM | 200,000 | $0.00 | $0.00 | 342,361 |
| Valamehr Bahram | Chief R&D Officer | 07/29/2024 | AA | Direct | COM | 200,000 | $0.00 | $0.00 | 358,069 |
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Transaction Type Key First letter: A = Acquired, D = Disposed Second letter: A = Grant, award or other acquisition pursuant to Rule 16b-3(d) C = Conversion of derivative security | D = Disposition to the issuer of issuer equity securities pursuant to Rule 16b-3(e) | E = Expiration of short derivative position | F = Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3. | G = Gift | H = Expiration (or cancellation) of long derivative position with value received | I = Discretionary transaction in accordance with Rule 16b-3(f) | J = Other | L = Small acquisition under Rule 16a-6 | M = Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 | O = Exercise of out-of-the-money derivative security | P = Open market or private purchase | S = Open market or private sale | U = Disposition pursuant to a tender of shares in a change of control transaction | W = Acquisition or disposition by will or the laws of descent and distribution | X = Exercise of in-the-money or at-the-money derivative security | Z = Deposit into or withdrawal from voting trust |
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