| Transactions | |||
| All | Buy | Sell | Option Exercise |
Filer's Name |
Relationship/ Title |
Trans. Date |
Trans. Type |
Ownership Type |
Security Type |
Shares |
Price |
Trans. Value |
Total Shares Owned |
| Lee Tien-Li | Chief Executive Officer | 12/11/2025 | AP | Direct | COM | 7,000 | $14.49 | $101,395.00 | 1,551,613 |
| Sun Nelson | Chief Financial Officer | 12/11/2025 | AP | Direct | COM | 3,000 | $14.40 | $43,200.00 | 108,484 |
| Jones Bryan | Chief Operating Officer | 10/15/2025 | AM | Direct | COM | 1,250 | $4.24 | $5,300.00 | 1,250 |
| Lee Tien-Li | Chief Executive Officer | 10/15/2025 | AM | Direct | COM | 1,229 | $4.24 | $5,210.96 | 1,544,613 |
| Lee Tien-Li | Chief Executive Officer | 09/15/2025 | AP | Direct | COM | 3,500 | $9.94 | $34,804.70 | 1,543,384 |
| Lee Tien-Li | Chief Executive Officer | 09/15/2025 | AP | Direct | COM | 6,500 | $9.51 | $61,818.90 | 1,539,884 |
| Lee Tien-Li | Chief Executive Officer | 09/12/2025 | AP | Direct | COM | 5,000 | $8.50 | $42,515.50 | 1,533,384 |
| Lee Tien-Li | Chief Executive Officer | 09/11/2025 | AP | Direct | COM | 6,000 | $7.82 | $46,926.00 | 1,528,384 |
| Lee Tien-Li | Chief Executive Officer | 09/10/2025 | AP | Direct | COM | 9,000 | $7.91 | $71,212.50 | 1,522,384 |
| Sun Nelson | Chief Financial Officer | 09/09/2025 | AP | Direct | COM | 6,000 | $8.07 | $48,439.80 | 105,484 |
| Lee Tien-Li | Chief Executive Officer | 08/28/2025 | AM | Direct | COM | 17,209 | $4.24 | $72,966.16 | 1,513,384 |
| Cormorant Asset Management, Lp | Other | 02/14/2025 | AP | Indirect | COM | 187,500 | $16.00 | $3,000,000.00 | 987,689 |
| Cormorant Asset Management, Lp | Other | 02/14/2025 | AC | Indirect | COM | 800,189 | $0.00 | $0.00 | 800,189 |
| Sun Nelson | Chief Financial Officer | 02/14/2025 | AP | Direct | COM | 10,000 | $16.00 | $160,000.00 | 99,484 |
| Sun Nelson | Chief Financial Officer | 02/14/2025 | AC | Direct | COM | 7,001 | $0.00 | $0.00 | 89,484 |
| Lee Tien-Li | Chief Executive Officer | 02/14/2025 | AP | Direct | COM | 16,542 | $16.00 | $264,672.00 | 1,496,175 |
| Lee Tien-Li | Chief Executive Officer | 02/14/2025 | AC | Direct | COM | 41,303 | $0.00 | $0.00 | 1,479,633 |
| Vickers Venture Fund Vi Pte Ltd | Other | 02/14/2025 | AC | Indirect | COM | 413,491 | $0.00 | $0.00 | 2,050,902 |
| Vickers Venture Fund Vi Pte Ltd | Other | 02/14/2025 | AC | Indirect | COM | 1,637,411 | $0.00 | $0.00 | 1,637,411 |
| Chi Jeffrey | Director | 02/14/2025 | AC | Indirect | COM | 133,364 | $0.00 | $0.00 | 133,364 |
| Decheng Capital Global Life Sciences Fund Iv, L.P. | Other | 02/14/2025 | AP | Indirect | COM | 625,000 | $16.00 | $10,000,000.00 | 958,412 |
| Decheng Capital Global Life Sciences Fund Iv, L.P. | Other | 02/14/2025 | AP | Indirect | COM | 625,000 | $16.00 | $10,000,000.00 | 2,958,887 |
| Decheng Capital Global Life Sciences Fund Iv, L.P. | Other | 02/14/2025 | AC | Indirect | COM | 333,412 | $0.00 | $0.00 | 333,412 |
| Decheng Capital Global Life Sciences Fund Iv, L.P. | Other | 02/14/2025 | AC | Indirect | COM | 2,333,887 | $0.00 | $0.00 | 2,333,887 |
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Transaction Type Key First letter: A = Acquired, D = Disposed Second letter: A = Grant, award or other acquisition pursuant to Rule 16b-3(d) C = Conversion of derivative security | D = Disposition to the issuer of issuer equity securities pursuant to Rule 16b-3(e) | E = Expiration of short derivative position | F = Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3. | G = Gift | H = Expiration (or cancellation) of long derivative position with value received | I = Discretionary transaction in accordance with Rule 16b-3(f) | J = Other | L = Small acquisition under Rule 16a-6 | M = Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 | O = Exercise of out-of-the-money derivative security | P = Open market or private purchase | S = Open market or private sale | U = Disposition pursuant to a tender of shares in a change of control transaction | W = Acquisition or disposition by will or the laws of descent and distribution | X = Exercise of in-the-money or at-the-money derivative security | Z = Deposit into or withdrawal from voting trust |
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