QUODD

Insider: RTW INVESTMENTS, LP

Company Holdings	All	OBIO	RCKT	RNA	TARS	ATHA	MIST	TELA	STOK

Company Holdings

All

OBIO

RCKT

RNA

TARS

ATHA

MIST

TELA

STOK

	Direct	Indirect Ownership	Total
Shares		44,410,852	44,410,852
Value	$	$501,657,894.00	$501,657,894.00

Ticker	Trans. Date	Trans. Type	Shares	Ownership Type	Issue Type	Price	Trans. Value	Total Shares Owned
OBIO	04/30/2025	AAP	49,900	Indirect	COM	$2.99	$149,201.00	8,306,063
OBIO	04/29/2025	AAP	50,000	Indirect	COM	$2.53	$126,500.00	8,256,163
RCKT	10/06/2022	AAP	1,355,932	Indirect	COM	$14.75	$19,999,997.00	17,628,567
RNA	08/04/2021	AAP	800,000	Indirect	COM	$18.00	$14,400,000.00	4,795,000
RCKT	05/11/2021	DDS	725,000	Indirect	COM	$40.03	$29,023,490.00	15,460,119
TARS	05/07/2021	DDS	450,000	Indirect	COM	$29.98	$13,491,000.00	2,013,601
RCKT	12/10/2020	AAP	247,720	Indirect	COM	$56.00	$13,872,320.00	17,530,044
ATHA	09/18/2020	AAP	750,000	Indirect	COM	$17.00	$12,750,000.00	2,668,913
RNA	06/16/2020	AAP	950,000	Indirect	COM	$18.00	$17,100,000.00	3,995,000
MIST	03/19/2020	AAP	5,870	Indirect	COM	$10.87	$63,803.97	4,315,102
MIST	03/18/2020	AAP	2,705	Indirect	COM	$10.36	$28,028.67	4,309,232
MIST	03/02/2020	AAP	78,263	Indirect	COM	$18.95	$1,483,083.85	4,306,527
MIST	01/13/2020	AAP	270,000	Indirect	COM	$16.25	$4,387,500.00	4,228,264
MIST	12/31/2019	AAP	21,438	Indirect	COM	$15.50	$332,340.45	3,958,264
MIST	12/30/2019	AAP	1,333	Indirect	COM	$15.48	$20,637.77	3,936,826
TELA	12/17/2019	DDS	36,000	Indirect	COM	$11.32	$407,617.20	1,139,358
TELA	12/13/2019	AAP	23,900	Indirect	COM	$11.60	$277,120.50	1,175,358
RCKT	12/10/2019	AAP	225,000	Indirect	COM	$22.25	$5,006,250.00	17,282,324
MIST	11/20/2019	AAP	400,000	Indirect	COM	$16.00	$6,400,000.00	3,935,493
STOK	11/08/2019	DDS	16,434	Indirect	COM	$28.70	$471,631.15	3,544,248
STOK	11/04/2019	AAP	104,873	Indirect	COM	$29.24	$3,066,843.09	3,560,682
STOK	11/01/2019	AAP	8,598	Indirect	COM	$28.61	$245,950.09	3,455,809
STOK	10/31/2019	AAP	18,747	Indirect	COM	$28.15	$527,658.69	3,447,211
STOK	10/30/2019	AAP	41,438	Indirect	COM	$28.79	$1,193,004.16	3,428,464
MIST	10/03/2019	AAP	1,908	Indirect	COM	$18.31	$34,939.87	3,530,006

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Trans. Date	Trans. Type	Shares	Ownership Type	Issue Type	Price	Trans. Value	Total Shares Owned
04/30/2025	AAP	49,900	Indirect	COM	$2.99	$149,201.00	8,306,063
04/29/2025	AAP	50,000	Indirect	COM	$2.53	$126,500.00	8,256,163

Trans. Date	Trans. Type	Shares	Ownership Type	Issue Type	Price	Trans. Value	Total Shares Owned
10/06/2022	AAP	1,355,932	Indirect	COM	$14.75	$19,999,997.00	17,628,567
05/11/2021	DDS	725,000	Indirect	COM	$40.03	$29,023,490.00	15,460,119
12/10/2020	AAP	247,720	Indirect	COM	$56.00	$13,872,320.00	17,530,044
12/10/2019	AAP	225,000	Indirect	COM	$22.25	$5,006,250.00	17,282,324
04/16/2019	AAP	550,005	Indirect	COM	$17.50	$9,625,087.50	17,057,324

Trans. Date	Trans. Type	Shares	Ownership Type	Issue Type	Price	Trans. Value	Total Shares Owned
08/04/2021	AAP	800,000	Indirect	COM	$18.00	$14,400,000.00	4,795,000
06/16/2020	AAP	950,000	Indirect	COM	$18.00	$17,100,000.00	3,995,000

Trans. Date	Trans. Type	Shares	Ownership Type	Issue Type	Price	Trans. Value	Total Shares Owned
05/07/2021	DDS	450,000	Indirect	COM	$29.98	$13,491,000.00	2,013,601

Trans. Date	Trans. Type	Shares	Ownership Type	Issue Type	Price	Trans. Value	Total Shares Owned
09/18/2020	AAP	750,000	Indirect	COM	$17.00	$12,750,000.00	2,668,913

Trans. Date	Trans. Type	Shares	Ownership Type	Issue Type	Price	Trans. Value	Total Shares Owned
03/19/2020	AAP	5,870	Indirect	COM	$10.87	$63,803.97	4,315,102
03/18/2020	AAP	2,705	Indirect	COM	$10.36	$28,028.67	4,309,232
03/02/2020	AAP	78,263	Indirect	COM	$18.95	$1,483,083.85	4,306,527
01/13/2020	AAP	270,000	Indirect	COM	$16.25	$4,387,500.00	4,228,264
12/31/2019	AAP	21,438	Indirect	COM	$15.50	$332,340.45	3,958,264
12/30/2019	AAP	1,333	Indirect	COM	$15.48	$20,637.77	3,936,826
11/20/2019	AAP	400,000	Indirect	COM	$16.00	$6,400,000.00	3,935,493
10/03/2019	AAP	1,908	Indirect	COM	$18.31	$34,939.87	3,530,006
10/01/2019	AAP	6,242	Indirect	COM	$17.63	$110,038.97	3,528,098
05/09/2019	AAP	666,667	Indirect	COM	$15.00	$10,000,005.00	3,521,856

Trans. Date	Trans. Type	Shares	Ownership Type	Issue Type	Price	Trans. Value	Total Shares Owned
12/17/2019	DDS	36,000	Indirect	COM	$11.32	$407,617.20	1,139,358
12/13/2019	AAP	23,900	Indirect	COM	$11.60	$277,120.50	1,175,358

Trans. Date	Trans. Type	Shares	Ownership Type	Issue Type	Price	Trans. Value	Total Shares Owned
11/08/2019	DDS	16,434	Indirect	COM	$28.70	$471,631.15	3,544,248
11/04/2019	AAP	104,873	Indirect	COM	$29.24	$3,066,843.09	3,560,682
11/01/2019	AAP	8,598	Indirect	COM	$28.61	$245,950.09	3,455,809
10/31/2019	AAP	18,747	Indirect	COM	$28.15	$527,658.69	3,447,211
10/30/2019	AAP	41,438	Indirect	COM	$28.79	$1,193,004.16	3,428,464
10/01/2019	AAP	31,560	Indirect	COM	$21.96	$693,029.20	3,387,026
06/19/2019	AAP	555,556	Indirect	COM	$18.00	$10,000,008.00	3,355,466

Transaction Type Key
First letter: A = Acquired, D = Disposed
Second letter:
A = Grant, award or other acquisition pursuant to Rule 16b-3(d) C = Conversion of derivative security | D = Disposition to the issuer of issuer equity securities pursuant to Rule 16b-3(e) | E = Expiration of short derivative position | F = Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3. | G = Gift | H = Expiration (or cancellation) of long derivative position with value received | I = Discretionary transaction in accordance with Rule 16b-3(f) | J = Other | L = Small acquisition under Rule 16a-6 | M = Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 | O = Exercise of out-of-the-money derivative security | P = Open market or private purchase | S = Open market or private sale | U = Disposition pursuant to a tender of shares in a change of control transaction | W = Acquisition or disposition by will or the laws of descent and distribution | X = Exercise of in-the-money or at-the-money derivative security | Z = Deposit into or withdrawal from voting trust

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