QUODD

Insider: Currie Mark G

Company Holdings	All	IRWD	CYCN

Company Holdings

All

IRWD

CYCN

	Direct	Indirect Ownership	Total
Shares	773,406	0	773,406
Value	$1,336,286.71	$0.00	$1,336,286.71

Ticker	Trans. Date	Trans. Type	Shares	Ownership Type	Issue Type	Price	Trans. Value	Total Shares Owned
IRWD	08/11/2022	DDS	70,000	Direct	COM	$11.78	$824,600.00	521,758
IRWD	06/14/2021	DDS	23,571	Direct	COM	$11.59	$273,187.89	570,187
CYCN	12/28/2020	DDS	20,107	Direct	COM	$3.01	$60,522.07	251,648
IRWD	01/23/2020	DDS	60,000	Direct	COM	$12.59	$755,400.00	549,272
IRWD	01/16/2020	DDS	8,888	Direct	COM	$12.80	$113,766.40	549,272
CYCN	12/30/2019	DDS	25,000	Direct	COM	$2.48	$62,000.00	271,755
CYCN	12/27/2019	DDS	25,000	Direct	COM	$2.55	$63,750.00	296,755
IRWD	05/10/2019	DDS	4,055	Direct	COM	$10.53	$42,699.15	528,903
CYCN	04/02/2019	AAP	270,107	Direct	COM	$14.81	$4,000,284.67	321,755
IRWD	03/08/2019	DDS	49,500	Direct	COM	$13.15	$650,925.00	528,480
IRWD	03/07/2019	DDS	225,500	Direct	COM	$13.29	$2,996,895.00	577,980
IRWD	02/21/2019	DDS	13	Direct	COM	$14.32	$186.16	803,480
IRWD	02/20/2019	DDS	1,631	Direct	COM	$14.31	$23,339.61	803,493
IRWD	10/05/2018	DDS	116,651	Direct	COM	$17.53	$2,044,892.03	30,124
IRWD	10/04/2018	DDS	94,456	Direct	COM	$17.94	$1,694,540.64	52,318
IRWD	10/04/2018	DDS	22,194	Direct	COM	$18.75	$416,137.50	30,124
IRWD	08/24/2018	DDS	65,000	Direct	COM	$18.39	$1,195,350.00	775,000
IRWD	08/23/2018	DDS	65,000	Direct	COM	$18.39	$1,195,350.00	775,000
IRWD	08/22/2018	DDS	65,000	Direct	COM	$18.51	$1,203,150.00	775,000
IRWD	02/21/2018	DDS	1,634	Direct	COM	$14.66	$23,954.44	18,124
IRWD	01/24/2018	DDS	60,000	Direct	COM	$15.45	$927,000.00	775,000
IRWD	03/14/2017	DDS	60,000	Direct	COM	$17.06	$1,023,600.00	775,000
IRWD	02/22/2017	DDS	1,800	Direct	COM	$16.94	$30,492.00	21,258
IRWD	03/09/2016	DDS	150,000	Direct	COM	$10.86	$1,629,000.00	374,102
IRWD	02/24/2016	DDS	2,154	Direct	COM	$8.50	$18,309.00	25,558

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Trans. Date	Trans. Type	Shares	Ownership Type	Issue Type	Price	Trans. Value	Total Shares Owned
08/11/2022	DDS	70,000	Direct	COM	$11.78	$824,600.00	521,758
06/14/2021	DDS	23,571	Direct	COM	$11.59	$273,187.89	570,187
01/23/2020	DDS	60,000	Direct	COM	$12.59	$755,400.00	549,272
01/16/2020	DDS	8,888	Direct	COM	$12.80	$113,766.40	549,272
05/10/2019	DDS	4,055	Direct	COM	$10.53	$42,699.15	528,903
03/08/2019	DDS	49,500	Direct	COM	$13.15	$650,925.00	528,480
03/07/2019	DDS	225,500	Direct	COM	$13.29	$2,996,895.00	577,980
02/21/2019	DDS	13	Direct	COM	$14.32	$186.16	803,480
02/20/2019	DDS	1,631	Direct	COM	$14.31	$23,339.61	803,493
10/05/2018	DDS	116,651	Direct	COM	$17.53	$2,044,892.03	30,124
10/04/2018	DDS	94,456	Direct	COM	$17.94	$1,694,540.64	52,318
10/04/2018	DDS	22,194	Direct	COM	$18.75	$416,137.50	30,124
08/24/2018	DDS	65,000	Direct	COM	$18.39	$1,195,350.00	775,000
08/23/2018	DDS	65,000	Direct	COM	$18.39	$1,195,350.00	775,000
08/22/2018	DDS	65,000	Direct	COM	$18.51	$1,203,150.00	775,000
02/21/2018	DDS	1,634	Direct	COM	$14.66	$23,954.44	18,124
01/24/2018	DDS	60,000	Direct	COM	$15.45	$927,000.00	775,000
03/14/2017	DDS	60,000	Direct	COM	$17.06	$1,023,600.00	775,000
02/22/2017	DDS	1,800	Direct	COM	$16.94	$30,492.00	21,258
03/09/2016	DDS	150,000	Direct	COM	$10.86	$1,629,000.00	374,102
02/24/2016	DDS	2,154	Direct	COM	$8.50	$18,309.00	25,558
02/24/2016	DDS	150,000	Direct	COM	$8.53	$1,279,500.00	374,102
02/19/2015	DDS	25,000	Direct	COM	$15.67	$391,750.00	310,000
11/13/2014	DDS	20,000	Direct	COM	$13.63	$272,600.00	310,000
05/22/2014	DDS	25,000	Direct	COM	$13.93	$348,250.00	310,000

Trans. Date	Trans. Type	Shares	Ownership Type	Issue Type	Price	Trans. Value	Total Shares Owned
12/28/2020	DDS	20,107	Direct	COM	$3.01	$60,522.07	251,648
12/30/2019	DDS	25,000	Direct	COM	$2.48	$62,000.00	271,755
12/27/2019	DDS	25,000	Direct	COM	$2.55	$63,750.00	296,755
04/02/2019	AAP	270,107	Direct	COM	$14.81	$4,000,284.67	321,755

Transaction Type Key
First letter: A = Acquired, D = Disposed
Second letter:
A = Grant, award or other acquisition pursuant to Rule 16b-3(d) C = Conversion of derivative security | D = Disposition to the issuer of issuer equity securities pursuant to Rule 16b-3(e) | E = Expiration of short derivative position | F = Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3. | G = Gift | H = Expiration (or cancellation) of long derivative position with value received | I = Discretionary transaction in accordance with Rule 16b-3(f) | J = Other | L = Small acquisition under Rule 16a-6 | M = Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 | O = Exercise of out-of-the-money derivative security | P = Open market or private purchase | S = Open market or private sale | U = Disposition pursuant to a tender of shares in a change of control transaction | W = Acquisition or disposition by will or the laws of descent and distribution | X = Exercise of in-the-money or at-the-money derivative security | Z = Deposit into or withdrawal from voting trust

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