QUODD

Insider: Boxer Capital, LLC

Company Holdings	All	TNGX	RAIN	TYRA	PMVP	SLDB	ESPR

Company Holdings

All

TNGX

RAIN

TYRA

PMVP

SLDB

ESPR

	Direct	Indirect Ownership	Total
Shares	21,350,735	693,524	22,044,259
Value	$185,257,785.73	$5,915,759.72	$191,173,545.45

Ticker	Trans. Date	Trans. Type	Shares	Ownership Type	Issue Type	Price	Trans. Value	Total Shares Owned
TNGX	10/16/2023	AAP	500,000	Direct	COM	$6.84	$3,420,000.00	8,198,642
TNGX	10/13/2023	AAP	750,000	Direct	COM	$7.07	$5,302,500.00	7,698,642
TNGX	10/09/2023	DDS	50,000	Indirect	COM	$9.91	$495,500.00	693,524
TNGX	10/09/2023	DDS	175,000	Direct	COM	$9.97	$1,744,750.00	6,948,642
TNGX	08/11/2023	AAP	475,000	Indirect	COM	$5.15	$2,446,250.00	743,542
RAIN	05/22/2023	DDS	995,000	Direct	COM	$1.25	$1,243,750.00	1,152,212
TNGX	10/13/2022	AAP	70,000	Direct	COM	$4.65	$325,227.00	7,123,642
TNGX	10/12/2022	AAP	50,000	Direct	COM	$4.43	$221,640.00	268,524
TNGX	10/11/2022	AAP	117,000	Direct	COM	$4.25	$497,706.30	218,524
TNGX	10/06/2022	AAP	70,394	Direct	COM	$4.06	$286,067.14	7,053,642
TNGX	10/05/2022	AAP	45,500	Direct	COM	$3.93	$178,642.10	6,942,748
TNGX	10/05/2022	AAP	40,500	Direct	COM	$3.84	$155,410.65	6,983,248
TNGX	10/04/2022	AAP	25,606	Direct	COM	$3.67	$93,976.58	6,897,248
TYRA	12/17/2021	AAP	125,000	Direct	COM	$13.12	$1,640,312.50	6,448,359
TYRA	09/17/2021	AAP	625,000	Direct	COM	$16.00	$10,000,000.00	6,323,359
RAIN	04/27/2021	AAP	1,025,000	Direct	COM	$17.00	$17,425,000.00	1,175,000
RAIN	04/23/2021	AAP	25,000	Direct	COM	$15.58	$389,500.00	25,000
RAIN	04/23/2021	AAP	125,000	Direct	COM	$16.27	$2,033,750.00	150,000
PMVP	09/25/2020	AAP	950,000	Direct	COM	$18.00	$17,100,000.00	950,000
SLDB	03/28/2019	DDS	60,000	Direct	COM	$9.53	$571,800.00	3,473,272
SLDB	03/27/2019	DDS	115,000	Direct	COM	$9.60	$1,104,000.00	3,533,272
SLDB	03/26/2019	DDS	275,000	Direct	COM	$10.08	$2,772,000.00	3,648,272
ESPR	11/05/2018	DDS	6,500	Direct	COM	$56.19	$365,235.00	1,128,250
ESPR	11/05/2018	DDS	2,000	Direct	COM	$57.38	$114,760.00	1,126,250
ESPR	11/05/2018	DDS	26,500	Direct	COM	$55.21	$1,463,065.00	1,134,750

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Trans. Date	Trans. Type	Shares	Ownership Type	Issue Type	Price	Trans. Value	Total Shares Owned
10/16/2023	AAP	500,000	Direct	COM	$6.84	$3,420,000.00	8,198,642
10/13/2023	AAP	750,000	Direct	COM	$7.07	$5,302,500.00	7,698,642
10/09/2023	DDS	50,000	Indirect	COM	$9.91	$495,500.00	693,524
10/09/2023	DDS	175,000	Direct	COM	$9.97	$1,744,750.00	6,948,642
08/11/2023	AAP	475,000	Indirect	COM	$5.15	$2,446,250.00	743,542
10/13/2022	AAP	70,000	Direct	COM	$4.65	$325,227.00	7,123,642
10/12/2022	AAP	50,000	Direct	COM	$4.43	$221,640.00	268,524
10/11/2022	AAP	117,000	Direct	COM	$4.25	$497,706.30	218,524
10/06/2022	AAP	70,394	Direct	COM	$4.06	$286,067.14	7,053,642
10/05/2022	AAP	45,500	Direct	COM	$3.93	$178,642.10	6,942,748
10/05/2022	AAP	40,500	Direct	COM	$3.84	$155,410.65	6,983,248
10/04/2022	AAP	25,606	Direct	COM	$3.67	$93,976.58	6,897,248

Trans. Date	Trans. Type	Shares	Ownership Type	Issue Type	Price	Trans. Value	Total Shares Owned
05/22/2023	DDS	995,000	Direct	COM	$1.25	$1,243,750.00	1,152,212
04/27/2021	AAP	1,025,000	Direct	COM	$17.00	$17,425,000.00	1,175,000
04/23/2021	AAP	25,000	Direct	COM	$15.58	$389,500.00	25,000
04/23/2021	AAP	125,000	Direct	COM	$16.27	$2,033,750.00	150,000

Trans. Date	Trans. Type	Shares	Ownership Type	Issue Type	Price	Trans. Value	Total Shares Owned
12/17/2021	AAP	125,000	Direct	COM	$13.12	$1,640,312.50	6,448,359
09/17/2021	AAP	625,000	Direct	COM	$16.00	$10,000,000.00	6,323,359

Trans. Date	Trans. Type	Shares	Ownership Type	Issue Type	Price	Trans. Value	Total Shares Owned
09/25/2020	AAP	950,000	Direct	COM	$18.00	$17,100,000.00	950,000

Trans. Date	Trans. Type	Shares	Ownership Type	Issue Type	Price	Trans. Value	Total Shares Owned
03/28/2019	DDS	60,000	Direct	COM	$9.53	$571,800.00	3,473,272
03/27/2019	DDS	115,000	Direct	COM	$9.60	$1,104,000.00	3,533,272
03/26/2019	DDS	275,000	Direct	COM	$10.08	$2,772,000.00	3,648,272

Trans. Date	Trans. Type	Shares	Ownership Type	Issue Type	Price	Trans. Value	Total Shares Owned
11/05/2018	DDS	6,500	Direct	COM	$56.19	$365,235.00	1,128,250
11/05/2018	DDS	2,000	Direct	COM	$57.38	$114,760.00	1,126,250
11/05/2018	DDS	26,500	Direct	COM	$55.21	$1,463,065.00	1,134,750
11/05/2018	DDS	5,000	Direct	COM	$60.28	$301,400.00	1,101,250
11/05/2018	DDS	6,390	Direct	COM	$58.82	$375,859.80	1,119,860
11/05/2018	DDS	13,610	Direct	COM	$59.48	$809,522.80	1,106,250
11/02/2018	DDS	2,500	Direct	COM	$54.65	$136,625.00	1,198,750
11/02/2018	DDS	37,500	Direct	COM	$55.25	$2,071,875.00	1,161,250

Transaction Type Key
First letter: A = Acquired, D = Disposed
Second letter:
A = Grant, award or other acquisition pursuant to Rule 16b-3(d) C = Conversion of derivative security | D = Disposition to the issuer of issuer equity securities pursuant to Rule 16b-3(e) | E = Expiration of short derivative position | F = Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3. | G = Gift | H = Expiration (or cancellation) of long derivative position with value received | I = Discretionary transaction in accordance with Rule 16b-3(f) | J = Other | L = Small acquisition under Rule 16a-6 | M = Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 | O = Exercise of out-of-the-money derivative security | P = Open market or private purchase | S = Open market or private sale | U = Disposition pursuant to a tender of shares in a change of control transaction | W = Acquisition or disposition by will or the laws of descent and distribution | X = Exercise of in-the-money or at-the-money derivative security | Z = Deposit into or withdrawal from voting trust

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