QUODD

Insider: LEIDEN JEFFREY M

Company Holdings	All	VRTX	DGX

Company Holdings

All

VRTX

DGX

	Direct	Indirect Ownership	Total
Shares	15,994	0	15,994
Value	$4,928,748.78	$0.00	$4,928,748.78

Ticker	Trans. Date	Trans. Type	Shares	Ownership Type	Issue Type	Price	Trans. Value	Total Shares Owned
VRTX	08/30/2024	DDS	3,784	Direct	COM	$499.00	$1,888,216.00	9,994
VRTX	02/15/2024	DDS	4,655	Direct	COM	$419.16	$1,951,189.80	17,896
VRTX	02/14/2024	DDS	4,356	Direct	COM	$419.04	$1,825,338.24	22,551
VRTX	02/13/2024	DDS	737	Direct	COM	$419.13	$308,898.81	26,907
VRTX	02/12/2024	DDS	647	Direct	COM	$420.39	$271,992.33	27,644
VRTX	02/12/2024	DDS	2,009	Direct	COM	$419.22	$842,212.98	28,291
VRTX	01/08/2024	DDS	6,648	Direct	COM	$419.07	$2,785,977.36	2,423
VRTX	12/13/2023	DDS	13,254	Direct	COM	$399.41	$5,293,780.14	9,171
VRTX	12/13/2023	DDS	100	Direct	COM	$400.19	$40,019.00	9,071
VRTX	10/16/2023	DDS	12,962	Direct	COM	$374.00	$4,847,788.00	22,425
VRTX	05/08/2023	DDS	1,125	Direct	COM	$349.00	$392,625.00	35,387
VRTX	05/05/2023	DDS	708	Direct	COM	$349.38	$247,361.04	36,683
VRTX	05/05/2023	DDS	171	Direct	COM	$350.30	$59,901.30	36,512
VRTX	05/03/2023	DDS	2,008	Direct	COM	$349.22	$701,233.76	39,891
VRTX	05/03/2023	DDS	1,800	Direct	COM	$350.53	$630,954.00	38,091
VRTX	05/03/2023	DDS	700	Direct	COM	$351.59	$246,113.00	37,391
VRTX	05/02/2023	DDS	1,505	Direct	COM	$350.48	$527,472.40	42,199
VRTX	05/02/2023	DDS	4,645	Direct	COM	$349.48	$1,623,334.60	43,704
VRTX	05/02/2023	DDS	300	Direct	COM	$353.18	$105,954.00	41,899
VRTX	07/25/2022	DDS	13,869	Direct	COM	$279.44	$3,875,553.36	120,633
VRTX	07/25/2022	DDS	34,090	Direct	COM	$281.27	$9,588,494.30	53,560
VRTX	07/25/2022	DDS	32,983	Direct	COM	$280.37	$9,247,443.71	87,650
VRTX	07/25/2022	DDS	40,666	Direct	COM	$282.43	$11,485,298.38	12,894
VRTX	07/25/2022	DDS	10,471	Direct	COM	$283.42	$2,967,690.82	2,423
VRTX	06/30/2020	DDS	8,321	Direct	COM	$286.13	$2,380,887.73	11,698

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Trans. Date	Trans. Type	Shares	Ownership Type	Issue Type	Price	Trans. Value	Total Shares Owned
08/30/2024	DDS	3,784	Direct	COM	$499.00	$1,888,216.00	9,994
02/15/2024	DDS	4,655	Direct	COM	$419.16	$1,951,189.80	17,896
02/14/2024	DDS	4,356	Direct	COM	$419.04	$1,825,338.24	22,551
02/13/2024	DDS	737	Direct	COM	$419.13	$308,898.81	26,907
02/12/2024	DDS	647	Direct	COM	$420.39	$271,992.33	27,644
02/12/2024	DDS	2,009	Direct	COM	$419.22	$842,212.98	28,291
01/08/2024	DDS	6,648	Direct	COM	$419.07	$2,785,977.36	2,423
12/13/2023	DDS	13,254	Direct	COM	$399.41	$5,293,780.14	9,171
12/13/2023	DDS	100	Direct	COM	$400.19	$40,019.00	9,071
10/16/2023	DDS	12,962	Direct	COM	$374.00	$4,847,788.00	22,425
05/08/2023	DDS	1,125	Direct	COM	$349.00	$392,625.00	35,387
05/05/2023	DDS	708	Direct	COM	$349.38	$247,361.04	36,683
05/05/2023	DDS	171	Direct	COM	$350.30	$59,901.30	36,512
05/03/2023	DDS	2,008	Direct	COM	$349.22	$701,233.76	39,891
05/03/2023	DDS	1,800	Direct	COM	$350.53	$630,954.00	38,091
05/03/2023	DDS	700	Direct	COM	$351.59	$246,113.00	37,391
05/02/2023	DDS	1,505	Direct	COM	$350.48	$527,472.40	42,199
05/02/2023	DDS	4,645	Direct	COM	$349.48	$1,623,334.60	43,704
05/02/2023	DDS	300	Direct	COM	$353.18	$105,954.00	41,899
07/25/2022	DDS	13,869	Direct	COM	$279.44	$3,875,553.36	120,633
07/25/2022	DDS	34,090	Direct	COM	$281.27	$9,588,494.30	53,560
07/25/2022	DDS	32,983	Direct	COM	$280.37	$9,247,443.71	87,650
07/25/2022	DDS	40,666	Direct	COM	$282.43	$11,485,298.38	12,894
07/25/2022	DDS	10,471	Direct	COM	$283.42	$2,967,690.82	2,423
06/30/2020	DDS	8,321	Direct	COM	$286.13	$2,380,887.73	11,698

Trans. Date	Trans. Type	Shares	Ownership Type	Issue Type	Price	Trans. Value	Total Shares Owned
05/29/2018	DDS	1,644	Direct	COM	$105.61	$173,622.84	6,000
08/04/2017	DDS	296	Direct	COM	$106.66	$31,571.06	6,000
07/27/2017	DDS	1,304	Direct	COM	$108.73	$141,782.62	6,296
08/03/2016	DDS	800	Direct	COM	$85.66	$68,526.40	6,027
08/03/2016	DDS	1,206	Direct	COM	$85.62	$103,262.54	6,027
08/03/2016	DDS	718	Direct	COM	$85.65	$61,496.70	6,827
08/03/2016	DDS	1,563	Direct	COM	$85.65	$133,866.26	6,027
08/03/2016	DDS	1,747	Direct	COM	$85.57	$149,485.55	6,027
08/03/2016	DDS	311	Direct	COM	$85.61	$26,625.02	6,027

Transaction Type Key
First letter: A = Acquired, D = Disposed
Second letter:
A = Grant, award or other acquisition pursuant to Rule 16b-3(d) C = Conversion of derivative security | D = Disposition to the issuer of issuer equity securities pursuant to Rule 16b-3(e) | E = Expiration of short derivative position | F = Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3. | G = Gift | H = Expiration (or cancellation) of long derivative position with value received | I = Discretionary transaction in accordance with Rule 16b-3(f) | J = Other | L = Small acquisition under Rule 16a-6 | M = Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 | O = Exercise of out-of-the-money derivative security | P = Open market or private purchase | S = Open market or private sale | U = Disposition pursuant to a tender of shares in a change of control transaction | W = Acquisition or disposition by will or the laws of descent and distribution | X = Exercise of in-the-money or at-the-money derivative security | Z = Deposit into or withdrawal from voting trust

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