QUODD

Insider: KLEIN JOSEPH III

Company Holdings	All	IONS	BMRN	PDLI

Company Holdings

All

IONS

BMRN

PDLI

	Direct	Indirect Ownership	Total
Shares	88,529	4,000	92,529
Value	$3,003,953.31	$256,200.00	$3,260,153.31

Ticker	Trans. Date	Trans. Type	Shares	Ownership Type	Issue Type	Price	Trans. Value	Total Shares Owned
IONS	09/03/2025	DDS	28,000	Indirect	COM	$60.00	$1,680,000.00	0
IONS	09/03/2025	DDS	28,000	Indirect	COM	$60.00	$1,680,000.00	0
IONS	05/03/2024	DDS	682	Indirect	COM	$42.94	$29,288.42	4,000
IONS	05/03/2024	DDS	1,318	Indirect	COM	$42.57	$56,110.03	4,682
IONS	05/03/2024	DDS	1,269	Indirect	COM	$42.59	$54,043.54	2,731
IONS	05/03/2024	DDS	731	Indirect	COM	$42.98	$31,415.97	2,000
IONS	05/03/2024	DDS	1,070	Indirect	COM	$42.55	$45,525.61	930
IONS	05/03/2024	DDS	930	Indirect	COM	$42.90	$39,893.00	0
IONS	11/15/2023	DDS	2,000	Direct	COM	$50.00	$100,000.00	16,346
IONS	09/26/2023	DDS	2,000	Direct	COM	$45.13	$90,253.60	18,346
IONS	07/18/2023	DDS	3,555	Direct	COM	$42.00	$149,310.00	20,346
IONS	01/17/2023	DDS	2,000	Direct	COM	$40.00	$80,000.00	16,791
IONS	07/15/2022	DDS	689	Direct	COM	$37.74	$26,002.86	19,435
IONS	07/15/2022	DDS	644	Direct	COM	$38.78	$24,974.32	18,791
IONS	07/15/2021	DDS	4,334	Direct	COM	$35.30	$152,989.33	18,126
IONS	10/20/2020	DDS	2,889	Direct	COM	$46.86	$135,385.76	13,794
IONS	12/23/2019	DDS	1,000	Direct	COM	$61.87	$61,874.20	12,683
IONS	12/16/2019	DDS	1,000	Direct	COM	$65.45	$65,446.50	12,683
IONS	12/09/2019	DDS	1,000	Direct	COM	$63.74	$63,744.70	12,683
IONS	12/02/2019	DDS	1,000	Direct	COM	$64.08	$64,083.00	12,683
IONS	11/25/2019	DDS	812	Direct	COM	$62.90	$51,074.80	12,683
IONS	11/20/2019	DDS	2,000	Direct	COM	$60.00	$120,000.00	13,495
IONS	03/29/2018	DDS	2,000	Direct	COM	$46.15	$92,300.00	9,939
IONS	03/15/2018	DDS	900	Direct	COM	$50.45	$45,405.00	9,939
IONS	03/15/2018	DDS	900	Direct	COM	$51.59	$46,431.00	9,939

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Trans. Date	Trans. Type	Shares	Ownership Type	Issue Type	Price	Trans. Value	Total Shares Owned
09/03/2025	DDS	28,000	Indirect	COM	$60.00	$1,680,000.00	0
09/03/2025	DDS	28,000	Indirect	COM	$60.00	$1,680,000.00	0
05/03/2024	DDS	682	Indirect	COM	$42.94	$29,288.42	4,000
05/03/2024	DDS	1,318	Indirect	COM	$42.57	$56,110.03	4,682
05/03/2024	DDS	1,269	Indirect	COM	$42.59	$54,043.54	2,731
05/03/2024	DDS	731	Indirect	COM	$42.98	$31,415.97	2,000
05/03/2024	DDS	1,070	Indirect	COM	$42.55	$45,525.61	930
05/03/2024	DDS	930	Indirect	COM	$42.90	$39,893.00	0
11/15/2023	DDS	2,000	Direct	COM	$50.00	$100,000.00	16,346
09/26/2023	DDS	2,000	Direct	COM	$45.13	$90,253.60	18,346
07/18/2023	DDS	3,555	Direct	COM	$42.00	$149,310.00	20,346
01/17/2023	DDS	2,000	Direct	COM	$40.00	$80,000.00	16,791
07/15/2022	DDS	689	Direct	COM	$37.74	$26,002.86	19,435
07/15/2022	DDS	644	Direct	COM	$38.78	$24,974.32	18,791
07/15/2021	DDS	4,334	Direct	COM	$35.30	$152,989.33	18,126
10/20/2020	DDS	2,889	Direct	COM	$46.86	$135,385.76	13,794
12/23/2019	DDS	1,000	Direct	COM	$61.87	$61,874.20	12,683
12/16/2019	DDS	1,000	Direct	COM	$65.45	$65,446.50	12,683
12/09/2019	DDS	1,000	Direct	COM	$63.74	$63,744.70	12,683
12/02/2019	DDS	1,000	Direct	COM	$64.08	$64,083.00	12,683
11/25/2019	DDS	812	Direct	COM	$62.90	$51,074.80	12,683
11/20/2019	DDS	2,000	Direct	COM	$60.00	$120,000.00	13,495
03/29/2018	DDS	2,000	Direct	COM	$46.15	$92,300.00	9,939
03/15/2018	DDS	900	Direct	COM	$50.45	$45,405.00	9,939
03/15/2018	DDS	900	Direct	COM	$51.59	$46,431.00	9,939

Trans. Date	Trans. Type	Shares	Ownership Type	Issue Type	Price	Trans. Value	Total Shares Owned
03/08/2010	DDS	10,000	Direct	COM	$22.12	$221,227.00	35,000
03/05/2009	AAP	5,000	Direct	COM	$10.07	$50,363.00	42,500
03/03/2009	AAP	5,000	Direct	COM	$10.56	$52,817.50	37,500
02/24/2009	AAP	10,000	Direct	COM	$12.08	$120,784.00	32,500
03/03/2008	DDS	1,004	Direct	COM	$38.08	$38,232.32	37,496
03/03/2008	DDS	4,982	Direct	COM	$38.00	$189,316.00	30,000
03/03/2008	DDS	1,300	Direct	COM	$38.10	$49,530.00	38,700
03/03/2008	DDS	200	Direct	COM	$38.09	$7,618.00	38,500
03/03/2008	DDS	914	Direct	COM	$38.07	$34,795.98	36,582
03/03/2008	DDS	500	Direct	COM	$38.01	$19,005.00	34,982
03/03/2008	DDS	1,000	Direct	COM	$38.03	$38,030.00	35,482
03/03/2008	DDS	100	Direct	COM	$38.06	$3,806.00	36,482

Trans. Date	Trans. Type	Shares	Ownership Type	Issue Type	Price	Trans. Value	Total Shares Owned
11/04/2009	DDS	1,800	Direct	COM	$8.30	$14,940.00	37,183
11/04/2009	DDS	400	Direct	COM	$8.30	$3,318.00	38,983
11/04/2009	DDS	700	Direct	COM	$8.29	$5,804.75	39,383
11/04/2009	DDS	900	Direct	COM	$8.29	$7,461.00	40,083
11/04/2009	DDS	700	Direct	COM	$8.34	$5,839.75	16,983
11/04/2009	DDS	200	Direct	COM	$8.30	$1,660.50	36,983
11/04/2009	DDS	400	Direct	COM	$8.31	$3,324.00	36,583
11/04/2009	DDS	3,300	Direct	COM	$8.33	$27,489.00	26,983
11/04/2009	DDS	9,300	Direct	COM	$8.34	$77,562.00	17,683
11/04/2009	DDS	6,200	Direct	COM	$8.32	$51,584.00	30,383
11/04/2009	DDS	100	Direct	COM	$8.32	$832.25	30,283
05/20/2008	AAP	500	Direct	COM	$9.50	$4,750.00	10,000
05/06/2008	AAP	500	Direct	COM	$9.60	$4,800.00	9,500
04/21/2008	AAP	300	Direct	COM	$13.87	$4,161.00	8,800
04/21/2008	AAP	200	Direct	COM	$13.88	$2,776.00	9,000
04/07/2008	AAP	300	Direct	COM	$11.38	$3,413.85	8,500
04/07/2008	AAP	200	Direct	COM	$11.38	$2,276.00	8,200
03/20/2008	AAP	500	Direct	COM	$9.52	$4,760.00	8,000
03/06/2008	AAP	500	Direct	COM	$10.60	$5,300.00	7,500
02/20/2008	AAP	100	Direct	COM	$15.65	$1,564.95	7,000
02/20/2008	AAP	400	Direct	COM	$15.65	$6,260.00	6,900
02/06/2008	AAP	500	Direct	COM	$14.20	$7,100.00	6,500
01/22/2008	AAP	100	Direct	COM	$15.01	$1,501.00	6,000
01/22/2008	AAP	300	Direct	COM	$15.03	$4,509.00	5,900
01/22/2008	AAP	100	Direct	COM	$15.04	$1,504.00	5,600

Transaction Type Key
First letter: A = Acquired, D = Disposed
Second letter:
A = Grant, award or other acquisition pursuant to Rule 16b-3(d) C = Conversion of derivative security | D = Disposition to the issuer of issuer equity securities pursuant to Rule 16b-3(e) | E = Expiration of short derivative position | F = Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3. | G = Gift | H = Expiration (or cancellation) of long derivative position with value received | I = Discretionary transaction in accordance with Rule 16b-3(f) | J = Other | L = Small acquisition under Rule 16a-6 | M = Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 | O = Exercise of out-of-the-money derivative security | P = Open market or private purchase | S = Open market or private sale | U = Disposition pursuant to a tender of shares in a change of control transaction | W = Acquisition or disposition by will or the laws of descent and distribution | X = Exercise of in-the-money or at-the-money derivative security | Z = Deposit into or withdrawal from voting trust

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