QUODD

Insider: PARSHALL B LYNNE

Company Holdings	All	IONS	CYTK

Company Holdings

All

IONS

CYTK

	Direct	Indirect Ownership	Total
Shares	86,944	0	86,944
Value	$5,222,663.56	$0.00	$5,222,663.56

Ticker	Trans. Date	Trans. Type	Shares	Ownership Type	Issue Type	Price	Trans. Value	Total Shares Owned
IONS	09/02/2025	DDS	9,250	Direct	COM	$51.49	$476,282.50	66,344
IONS	09/02/2025	DDS	10,750	Direct	COM	$50.42	$542,015.00	75,594
IONS	08/06/2025	DDS	4,600	Direct	COM	$41.87	$192,595.10	86,744
IONS	08/06/2025	DDS	400	Direct	COM	$42.63	$17,051.00	86,344
CYTK	09/09/2024	DDS	5,000	Direct	COM	$54.92	$274,600.00	20,600
CYTK	08/26/2024	DDS	5,000	Direct	COM	$57.26	$286,300.00	20,600
CYTK	08/12/2024	DDS	5,000	Direct	COM	$55.20	$276,000.00	20,600
CYTK	07/29/2024	DDS	5,000	Direct	COM	$59.84	$299,200.00	20,600
CYTK	07/15/2024	DDS	5,000	Direct	COM	$55.82	$279,100.00	20,600
CYTK	07/01/2024	DDS	5,000	Direct	COM	$54.22	$271,100.00	20,600
CYTK	06/17/2024	DDS	5,000	Direct	COM	$52.55	$262,750.00	20,600
CYTK	06/03/2024	DDS	5,000	Direct	COM	$48.64	$243,200.00	15,600
IONS	12/28/2023	DDS	42,525	Direct	COM	$50.19	$2,134,223.44	82,588
IONS	12/27/2023	DDS	50,000	Direct	COM	$50.23	$2,511,515.00	82,588
IONS	12/26/2023	DDS	25,113	Direct	COM	$51.46	$1,292,390.32	82,588
IONS	09/26/2023	DDS	10,000	Direct	COM	$45.13	$451,268.00	82,588
CYTK	09/01/2022	DDS	30,296	Direct	COM	$52.79	$1,599,325.84	10,000
CYTK	11/05/2021	DDS	20,000	Direct	COM	$40.00	$800,000.00	5,000
CYTK	11/05/2021	DDS	4,032	Direct	COM	$40.00	$161,280.00	5,000
CYTK	11/05/2021	DDS	4,166	Direct	COM	$40.00	$166,640.00	5,000
CYTK	11/05/2021	DDS	2,798	Direct	COM	$40.00	$111,920.00	5,000
CYTK	10/19/2021	DDS	1,999	Direct	COM	$35.73	$71,432.87	5,000
CYTK	10/19/2021	DDS	8,333	Direct	COM	$35.73	$297,773.92	5,000
IONS	12/23/2020	DDS	10,000	Direct	COM	$60.00	$600,000.00	57,464
IONS	11/25/2020	DDS	3,590	Direct	COM	$50.05	$179,679.50	67,464

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Trans. Date	Trans. Type	Shares	Ownership Type	Issue Type	Price	Trans. Value	Total Shares Owned
09/02/2025	DDS	9,250	Direct	COM	$51.49	$476,282.50	66,344
09/02/2025	DDS	10,750	Direct	COM	$50.42	$542,015.00	75,594
08/06/2025	DDS	4,600	Direct	COM	$41.87	$192,595.10	86,744
08/06/2025	DDS	400	Direct	COM	$42.63	$17,051.00	86,344
12/28/2023	DDS	42,525	Direct	COM	$50.19	$2,134,223.44	82,588
12/27/2023	DDS	50,000	Direct	COM	$50.23	$2,511,515.00	82,588
12/26/2023	DDS	25,113	Direct	COM	$51.46	$1,292,390.32	82,588
09/26/2023	DDS	10,000	Direct	COM	$45.13	$451,268.00	82,588
12/23/2020	DDS	10,000	Direct	COM	$60.00	$600,000.00	57,464
11/25/2020	DDS	3,590	Direct	COM	$50.05	$179,679.50	67,464
11/24/2020	DDS	710	Direct	COM	$50.82	$36,082.20	67,464
11/23/2020	DDS	3,200	Direct	COM	$50.12	$160,384.00	67,464
04/29/2019	DDS	50,000	Direct	COM	$75.01	$3,750,635.00	52,677
03/12/2019	DDS	8,334	Direct	COM	$75.00	$625,050.00	52,677
02/27/2019	DDS	8,333	Direct	COM	$70.00	$583,310.00	52,677
01/16/2018	DDS	5,986	Direct	COM	$51.76	$309,835.36	38,180
10/18/2017	DDS	7,785	Direct	COM	$65.00	$506,025.00	25,741
10/18/2017	DDS	8,333	Direct	COM	$65.00	$541,645.00	25,741
03/01/2017	DDS	4,625	Direct	COM	$49.26	$227,827.50	25,651
01/17/2017	DDS	1,509	Direct	COM	$46.29	$69,850.86	20,422
01/17/2017	DDS	965	Direct	COM	$46.29	$44,670.04	18,494
01/17/2017	DDS	2,696	Direct	COM	$46.29	$124,796.49	23,245
01/17/2017	DDS	2,076	Direct	COM	$46.29	$96,096.59	25,651
12/15/2016	DDS	1,000	Indirect	COM	$50.00	$50,000.00	0
12/15/2016	DDS	1,000	Indirect	COM	$50.00	$50,000.00	0

Trans. Date	Trans. Type	Shares	Ownership Type	Issue Type	Price	Trans. Value	Total Shares Owned
09/09/2024	DDS	5,000	Direct	COM	$54.92	$274,600.00	20,600
08/26/2024	DDS	5,000	Direct	COM	$57.26	$286,300.00	20,600
08/12/2024	DDS	5,000	Direct	COM	$55.20	$276,000.00	20,600
07/29/2024	DDS	5,000	Direct	COM	$59.84	$299,200.00	20,600
07/15/2024	DDS	5,000	Direct	COM	$55.82	$279,100.00	20,600
07/01/2024	DDS	5,000	Direct	COM	$54.22	$271,100.00	20,600
06/17/2024	DDS	5,000	Direct	COM	$52.55	$262,750.00	20,600
06/03/2024	DDS	5,000	Direct	COM	$48.64	$243,200.00	15,600
09/01/2022	DDS	30,296	Direct	COM	$52.79	$1,599,325.84	10,000
11/05/2021	DDS	20,000	Direct	COM	$40.00	$800,000.00	5,000
11/05/2021	DDS	4,032	Direct	COM	$40.00	$161,280.00	5,000
11/05/2021	DDS	4,166	Direct	COM	$40.00	$166,640.00	5,000
11/05/2021	DDS	2,798	Direct	COM	$40.00	$111,920.00	5,000
10/19/2021	DDS	1,999	Direct	COM	$35.73	$71,432.87	5,000
10/19/2021	DDS	8,333	Direct	COM	$35.73	$297,773.92	5,000
10/05/2020	DDS	4,375	Direct	COM	$30.00	$131,250.00	0
10/05/2020	DDS	20,000	Direct	COM	$30.00	$600,000.00	0
10/05/2020	DDS	20,000	Direct	COM	$30.00	$600,000.00	0
10/05/2020	DDS	5,936	Direct	COM	$30.00	$178,080.00	0
06/22/2020	DDS	10,000	Direct	COM	$25.00	$250,000.00	0
06/22/2020	DDS	6,510	Direct	COM	$25.00	$162,750.00	0

Transaction Type Key
First letter: A = Acquired, D = Disposed
Second letter:
A = Grant, award or other acquisition pursuant to Rule 16b-3(d) C = Conversion of derivative security | D = Disposition to the issuer of issuer equity securities pursuant to Rule 16b-3(e) | E = Expiration of short derivative position | F = Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3. | G = Gift | H = Expiration (or cancellation) of long derivative position with value received | I = Discretionary transaction in accordance with Rule 16b-3(f) | J = Other | L = Small acquisition under Rule 16a-6 | M = Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 | O = Exercise of out-of-the-money derivative security | P = Open market or private purchase | S = Open market or private sale | U = Disposition pursuant to a tender of shares in a change of control transaction | W = Acquisition or disposition by will or the laws of descent and distribution | X = Exercise of in-the-money or at-the-money derivative security | Z = Deposit into or withdrawal from voting trust

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